Professor Greg Stuart
BSc (Hons), PhD (Neuroscience)
Head, Neuronal Signalling Lab, JCSMR
ANU College of Health and Medicine
Areas of expertise
- Neurosciences 1109
Researcher's projects
- Processing of visual information in superior colliculus
- Dendritic properties of rodent and human neurons
- Integration of binocular visual information
- Role of superior colliculus in cortical coding
- Impact of somatic and dendritic inhibition on neuronal output
Publications
- Godenzini, L, Alwis, D, Guzulaitis, R et al. 2021, 'Auditory input enhances somatosensory encoding and tactile goal-directed behavior', Nature Communications, vol. 12, no. 1.
- To, M, HONNURAIAH, S & Stuart, G 2021, 'Voltage Clamp Errors During Estimation of Concurrent Excitatory and Inhibitory Synaptic Input to Neurons with Dendrites', Neuroscience, vol. 489, pp. 98-110.
- Gharaei, S, HONNURAIAH, S, Arabzadeh, E et al. 2020, 'Superior colliculus modulates cortical coding of somatosensory information', Nature Communications, vol. 11, no. 1, pp. 1693-.
- Hanlon, L, Gautam, V, Wood, J et al. 2020, 'Diamond nanopillar arrays for quantum microscopy of neuronal signals', Neurophotonics, vol. 7, no. 3, pp. 1-12.
- Loutit, A, Shivdasani, M, Maddess, T et al. 2019, 'Peripheral nerve activation evokes machine-learnable signals in the dorsal column nuclei', Frontiers in Systems Neuroscience, vol. 13, pp. 11: 1-19.
- Connelly, W & Stuart, G 2019, 'Local versus Global Dendritic Integration', Neuron, vol. 103, no. 2, pp. 173-174.
- Bock, T, HONNURAIAH, S & Stuart, G 2019, 'Paradoxical Excitatory Impact of SK Channels on Dendritic Excitability', Journal of Neuroscience, vol. 39, no. 40, pp. 7826-7839.
- Loutit, A, Maddess, T, Redmond, S et al. 2017, 'Characterisation and functional mapping of surface potentials in the rat dorsal column nuclei', Journal of Physiology, vol. 595, no. 13, pp. 4507-4524.
- Lissek, T, Adams, M, Adelman, J et al 2017, 'Building Bridges through Science', Neuron, vol. 96, no. 4, pp. 730-735pp.
- Jones, S, To, M & Stuart, G 2017, 'Dendritic small conductance calcium-activated potassium channels activated by action potentials suppress EPSPs and gate spike-timing dependent synaptic plasticity', eLife, vol. 6, pp. 18pp.
- Breton, J & Stuart, G 2017, 'GABAB receptors in neocortical and hippocampal pyramidal neurons are coupled to different potassium channels', European Journal of Neuroscience, vol. 46, no. 12, pp. 2859-2866pp.
- Bock, T & Stuart, G 2016, 'Impact of calcium-activated potassium channels on NMDA spikes in cortical layer 5 pyramidal neurons', Journal of Neurophysiology, vol. 115, no. 3, pp. 1740-1748.
- Bock, T & Stuart, G 2016, 'The impact of BK channels on cellular excitability depends on their subcellular location', Frontiers in Cellular Neuroscience, vol. 10, no. 206, pp. 8pp.
- Stuart, G & Spruston, N 2015, 'Dendritic integration: 60 years of progress', Nature Neuroscience, vol. 18, no. 12, pp. 1713-1721.
- Jones, S & Stuart, G 2013, 'Different calcium sources control somatic versus dendritic SK channel activation during action potentials', Journal of Neuroscience, vol. 33, no. 50, pp. 19396-19405.
- Spruston, N, Hausser, M & Stuart, G 2013, 'Information Processing in Dendrites and Spines', in (ed.), Fundamental Neuroscience, Academic Press, United Kingdom, pp. 231-259.
- Go, MA, To, M, Stricker, C, Redman, S, Bachor, H, Stuart, G, Daria, VR, 2013, 'Four-dimensional multi-site photolysis of caged neurotransmitters', Frontiers in Cellular Neuroscience, vol. 7, p231
- Longordo, F, To, M, Ikeda, K et al 2013, 'Sublinear integration underlies binocular processing in primary visual cortex', Nature Neuroscience, vol. 16, no. 6, pp. 714-723.
- Stuart, G 2012, 'Dendritic spikes veto inhibition', Neuron, vol. 75, no. 5, pp. 744-746.
- Kole, M & Stuart, G 2012, 'Signal Processing in the Axon Initial Segment', Neuron, vol. 73, no. 2, pp. 235-247.
- Breton, J & Stuart, G 2012, 'Somatic and dendritic GABAB receptors regulate neuronal excitability via different mechanisms', Journal of Neurophysiology, vol. 108, no. 10, pp. 2810-2818.
- Gulledge, A, Carnevale, N & Stuart, G 2012, 'Electrical advantages of dendritic spines', PLOS ONE (Public Library of Science), vol. 7, no. 4.
- Hallermann, S, de Kock, C, Stuart, G et al 2012, 'State and location dependence of action potential metabolic cost in cortical pyramidal neurons', Nature Neuroscience, vol. 15, no. 7, pp. 1007-1014.
- Palmer, L, Clark, B, Grundemann, J et al 2010, 'Initiation of simple and complex spikes in cerebellar Purkinje cells', Journal of Physiology, vol. 588, no. 10, pp. 1709-1717.
- Froemke, R, Letzkus, J, Kampa, B et al. 2010, 'Dendritic synapse location and neocortical spike-timing-dependent plasticity', Frontiers in Synaptic Neuroscience, vol. 2, no. JUL, pp. 29-29.
- Etherington, S, Atkinson, S, Stuart, G et al 2010, 'Synaptic integration', in Hildegard Kehrer-Sawatzki (ed.), Encyclopedia of Life Sciences (2010), John Wiley & Sons Inc, Chichester.
- Hausser, M, Spruston, N & Stuart, G 2008, 'Conclusion: The future of dendrite research', in Greg Stuart, Nelson Spruston, Michael Hausser (ed.), Dendrites (2nd ed), Oxford University Press, Oxford, pp. 551-554.
- Palmer, L & Stuart, G 2009, 'Membrane Potential Changes in Dendritic Spines during Action Potentials and Synaptic Input', Journal of Neuroscience, vol. 29, no. 21, pp. 6897-693.
- Breton, JD & Stuart, G 2009, 'Loss of sensory input increases the intrinsic excitability of layer 5 pyramidal neurons in rat barrel cortex.', Journal of Physiology, vol. 587, no. 21, pp. 5107-5119.
- Spruston, N, Stuart, G & Hausser, M 2008, 'Dendritic integration', in Greg Stuart, Nelson Spruston, Michael Hausser (ed.), Dendrites (2nd ed), Oxford University Press, Oxford, pp. 351-399.
- Kole, M, Ilschner, S, Kampa, B et al. 2008, 'Action potential generation requires a high sodium channel density in the axon initial segment', Nature Neuroscience, vol. 11, no. 2, pp. 178-186.
- Kole, M & Stuart, G 2008, 'Is action potential threshold lowest in the axon?', Nature Neuroscience, vol. 11, no. 11, pp. 1253-1255.
- Letzkus, J & Stuart, G 2008, 'All asleep - But Inhibition is Wide Awake', Neuron, vol. 57, no. 6, pp. 804-806.
- Stuart, G, Spruston, N & Hausser, M, eds, 2008, Dendrites (2nd ed), Oxford University Press, Oxford.
- Kampa, B, Letzkus, J & Stuart, G 2007, 'Dendritic mechanisms controlling spike-timing dependent synaptic plasticity', Trends in Neurosciences, vol. 30, no. 9, pp. 456-463.
- Letzkus, J, Kampa, B & Stuart, G 2007, 'Does spike-timing-dependent synaptic plasticity underlie memory formation?', Clinical and Experimental Pharmacology and Physiology, vol. 34, pp. 1070-1076.
- Kole, M, Brauer, A & Stuart, G 2007, 'Inherited cortical HCN1 loss amplifies dendritic calcium electrogenesis and burst firing in an rat absence epilepsy model', Journal of Physiology, vol. 578, pp. 507-528.
- Kole, M, Letzkus, J & Stuart, G 2007, 'Axon initial segment Kv1 channels control axonal action potential waveform and synaptic efficacy.', Neuron, vol. 55, pp. 633-647.
- Gulledge, A, Park, S, Kawaguchi, Y et al. 2007, 'Heterogeneity of Phasic Cholinergic Signaling in Neocortical Neurons', Journal of Neurophysiology, vol. 97, pp. 2215-2229.
- Kole, M, Hallermann, S & Stuart, G 2006, 'Single Ih channels in pyramidal neuron dendrites: Properties,distribution,and impact on action potential output', Journal of Neuroscience, vol. 26, no. 6, pp. 1677-1687.
- Letzkus, J, Kampa, B & Stuart, G 2006, 'Learning rules for spike timing-dependent plasticity depend on dendritic synapse location', Journal of Neuroscience, vol. 26, no. 41, pp. 10420-10429.
- Palmer, L & Stuart, G 2006, 'Site of action potential initiation in layer 5 pyramidal neurons', Journal of Neuroscience, vol. 26, no. 6, pp. 1854-1863.
- Davie, J, Kole, M, Letzkus, J et al 2006, 'Dendritic patch-clamp recording', Nature Protocols, vol. 1, no. 3, pp. 1235-1247.
- Kampa, B, Letzkus, J & Stuart, G 2006, 'Requirement of dendretic calcium spikes for induction of spike-timing-dependent synaptic plasticity', Journal of Physiology, vol. 574, no. 1, pp. 283-290.
- Kampa, B & Stuart, G 2006, 'Calcium spikes in basal dendrites of layer 5 pyramidal neurons during action potential bursts', Journal of Neuroscience, vol. 26, no. 28, pp. 7424-7432.
- Stuart, G & Palmer, L 2006, 'Imaging membrane potential in dendrites and axons of single neurons', Pflugers Archives European Journal of Physiology, vol. 453, pp. 403-410.
- Kampa, B, Letzkus, J & Stuart, G 2006, 'Cortical feed-forward networks for binding different streams of sensory information', Nature Neuroscience, vol. 9, no. 12, pp. 1472-1473.
- Gulledge, A & Stuart, G 2005, 'Cholinergic inhibition of neocortical pyramidal neurons', Journal of Neuroscience, vol. 25, no. 44, pp. 10308-10320.
- Kampa, B & Stuart, G 2005, 'NMDA receptor kinetics are tuned for spike-timing dependent synaptic plasticity', Physiology News, vol. 58, no. Spring 2005, pp. 29-30.
- Gulledge, A, Kampa, B & Stuart, G 2005, 'Synaptic Integration in Dendritic Trees', Journal of Neurobiology, vol. 64, no. 1, pp. 75-90.
- Kampa, B, Clements, J, Jonas, P et al. 2004, 'Kinetics of Mg2+ unblock of NMDA receptors: implications for spike-timing dependent synaptic plasticity', Journal of Physiology, vol. 556, no. 2, pp. 337-345.
- Williams, S & Stuart, G 2003, 'Role of dentritic synapse location in the control of action potential output', Trends in Neurosciences, vol. 26, no. 3, pp. 147-154.
- Gulledge, A & Stuart, G 2003, 'Action potential initiation and propagation in layer 5 pyramidal neurons of the rat prefrontal cortex: absence of dopamine modulation', Journal of Neuroscience, vol. 23, no. 36, pp. 11363-11372.
- Gulledge, A & Stuart, G 2003, 'Excitatory actions of GABA in the cortex', Neuron, vol. 37, no. 2, pp. 299-309.
- Williams, S & Stuart, G 2003, 'Voltage- and site-dependent control of the somatic impact of dendritic IPSPs', Journal of Neuroscience, vol. 23, no. 19, pp. 7358-7367.
- Williams, S & Stuart, G 2002, 'Dependence of EPSP efficacy on synapse location in neocortical pyramidal neurons', Science, vol. 295, pp. 1907-1910.
- Williams, S, Christensen, S, Stuart, G et al 2002, 'Membrane potential bistability is controlled by the hyperpolarization-activated current IH in rat cerebellar Purkinje neurons in vitro', Journal of Physiology, vol. 539, no. 2, pp. 469-483.
- Hausser, M, Major, G & Stuart, G 2001, 'Differential shunting of EPSPs by action potentials', Science, vol. 291, pp. 138-141.
- Stuart, G 2001, 'Determinants of spike timing-dependent synaptic plasticity', Neuron, vol. 32, no. 6, pp. 966-968.
- Stuart, G & Hausser, M 2001, 'Dendritic coincidence detection of EPSPs and action potentials', Nature Neuroscience, vol. 4, no. 1, pp. 63-71.
- Williams, S & Stuart, G 2000, 'Action potential backpropagation and somato-dendritic distribution of ion channels in thalamocortical neurons', Journal of Neuroscience, vol. 20, pp. 1307-1317.
- Williams, S & Stuart, G 2000, 'Site independence of EPSP time course is mediated by dendritic I(h) in neocortical pyramidal neurons', Journal of Neurophysiology, vol. 83, pp. 3177-3182.
- Williams, S & Stuart, G 2000, 'Backpropagation of physiological spike trains in neocortical pyramidal neurons: Implications for temporal coding in dendrites', Journal of Neuroscience, vol. 20, pp. 8238-8246.
- Hausser, M, Spruston, N & Stuart, G 2000, 'Diversity and Dynamics of Dendritic Signalling', Science, vol. 290, pp. 737-744.
- Gentet, L, Stuart, G & Clements, J 2000, 'Direct Measurement of Specific Membrane Capacitance in Neurons', Biophysical Journal, vol. 79, pp. 314-320.
- Stuart, G 1999, 'Voltage-activated sodium channels amplify inhibition in neocortical pyramidal neurons', Nature Neuroscience, vol. 2, pp. 144-150.
- Williams, S & Stuart, G 1999, 'Mechanisms and consequences of burst fring in rat neocortical pyramidal neurons', Journal of Physiology, vol. 521, pp. 467-448.
Projects and Grants
Grants information is drawn from ARIES. To add or update Projects or Grants information please contact your College Research Office.
- Probing the role of dendrites in cortical gain control - Externally led (Primary Investigator)
- Electrical properties of human dendrites (Primary Investigator)
- Upgrading 2-Photon microscope (35814 - GNT9000538) (Primary Investigator)
- Dendritic spikes in apical obliques of L5 pyramidal neurons (Secondary Investigator)
- Role of calcium-activated potassium channels in neuronal excitability, synaptic plasticity and sensory processing (Primary Investigator)
- Leica VT1200 S Fully Automated Vibrating Blade Microtome (See 32537) (Primary Investigator)
- Understanding the roles of dendritic domains in neuronal function (Secondary Investigator)
- Impact of inhibition on brain function (Primary Investigator)
- ARC Centre of Excellence for Integrative Brain Function (Secondary Investigator)
- Using light to probe brain activity in three dimensions (Secondary Investigator)
- Cortical mechanisms underlying binocular vision (Primary Investigator)
- Regulation of cortical excitability by GABAB receptors (Primary Investigator)
- Properties of dendritic spines and their role in synaptic plasticity (Primary Investigator)
- Investigating action potential initiation and propagation in neurons using voltage-sensitive dyes (Primary Investigator)
- Brain plasticity following changes in sensory input (Primary Investigator)
- Cellular mechanisms underlying absence epilepsy (Primary Investigator)
