Areas of expertise

• Autoimmunity 110703

Publications

• Kopprasch, S, Dheban, S, Schuhmann, K et al 2016, 'Detection of independent associations of plasma lipidomic parameters with insulin sensitivity indices using data mining methodology', PLOS ONE (Public Library of Science), vol. 11, no. 10, pp. e0164173-e0164173.
• Bogdani, M, Simeonovic, C, Nagy, N et al 2015, 'The Detection of Glycosaminoglycans in Pancreatic Islets and Lymphoid Tissues', Methods in Molecular Biology, vol. 1229, pp. 413-430.
• Choong, F, Freeman, C, Parish, C, Simeonovic CJ 2015, 'Islet Heparan Sulfate but Not Heparan Sulfate Proteoglycan Core Protein Is Lost During Islet Isolation and Undergoes Recovery Post-Islet Transplantation', American Journal of Transplantation, vol. 15, pp. 2861-2864.
• Delghingaro-Augusto, V, Madad, L, Chandra, A et al. 2014, 'Islet inflammation, hemosiderosis, and fibrosis in intrauterine growth-restricted and high fat-fed sprague-dawley rats', American Journal of Pathology, vol. 184, no. 5, pp. 1446-1457.
• Irving-Rodgers, H, Choong, F, Hummitzsch, K et al 2014, 'Pancreatic Islet basement membrane loss and remodeling after mouse islet isolation and transplantation: Impact for allograft rejection', Cell Transplantation, vol. 23, no. 1, pp. 59-72.
• Simeonovic, C & Parish, C 2013, 'Comment on: Korpos et al. The peri-islet basement membrane, a barrier to infiltrating leukocytes in type 1 diabetes in mouse and human. Diabetes 2013;62:531-542', Diabetes, vol. 62, no. 8, pp. e13-e13.
• Parish, C, Freeman, C, Ziolkowski, A, He YQ, Sutcliffe EL, Zafar A, Rao S, Simeonovic CJ. 2013, 'Unexpected new roles for heparanase in Type 1 diabetes and immune gene regulation', Matrix Biology, vol. 32, no. 5, pp. 228-233.
• Simeonovic, C, Ziolkowski, A, Wu, Z, Choong FJ, Freeman C, Parish CR. 2013, 'Heparanase and autoimmune diabetes', Frontiers in Immunology, vol. 4, pp. 1-7.
• Tait, B, Simeonovic, C & McCullagh, P 2012, 'Contributions of Australasians to the Study of Immune Responses to Allogeneic Transplanted Tissue', in Brian D Tait (ed.), More than a Footnote, Australian Scholarly Publishing Pty Ltd, Melbourne, pp. 465-489.
• Bogdani, M, Korpos, E, Simeonovic, C et al 2012, 'Extracellular Matrix Components in the Pathogenesis of Type 1 Diabetes', Current Diabetes Reports, vol. 14, no. 12, pp. 552-552.
• Ziolkowski AF, Popp SK, Freeman C, Parish CR, Simeonovic CJ. 2012, 'Heparan sulfate and heparanase play key roles in mouse β cell survival and autoimmune diabetes', Journal of Clinical Investigation, vol. 122, pp. 132-141.
• Schmid, J, Ludwig, B, Schally, A et al 2011, 'Modulation of pancreatic islets-stress axis by hypothalamic releasing hormones and 11 beta-hydroxysteroid dehydrogenase', PNAS - Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 33, pp. 13722-13727.
• Schmid, J, Ludwig, B, Schally, A et al 2011, 'Reply to Liu et al.: Hypothalamic control of islets', PNAS - Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 51, pp. E1391-E1391.
• Hodgson R, Christiansen D, Ziolkowski A, Mouhtouris E, Simeonovic CJ, Ierino FL, Sandrin MS 2011, 'Prolonged xenograft survival induced by inducible costimulator-Ig Is associated with increased Forkhead Box P3+ Cells', Transplantation, vol. 91, no. 10, pp. 1090-1097.
• Mulley, W, Li, Y, Wee, J et al 2008, 'Local expression of IDO, either alone or in combination with CD40Ig, IL10 or CTLA4Ig,inhibits indirect xenorejection responses', Xenotransplantation, vol. 15, no. 3, pp. 174-183.
• Irving-Rodgers, H, Ziolkowski, A, Parish, C et al 2008, 'Molecular composition of the peri-islet basement membrane in NOD mice: a barrier against destructive insulitis', Diabetologia, vol. 51, pp. 1680-1688.
• Popp, S, Mann, D, Milburn, P et al 2007, 'Transient transmission of porcine endogenous retrovirus to fetal lambs after pig islet tissue xenotransplantation', Immunology and Cell Biology, vol. 85, pp. 238-248.
• Solomon, M, Ramshaw, I & Simeonovic, C 2005, 'Recombinant fowlpox virus for in vitro gene delivery to pancreatic islet tissue', Immunology and Cell Biology, vol. 83, pp. 615-625.
• Simeonovic, C, Ziolkowski, A, Popp, S et al 2005, 'Porcine endogenous retrovirus encodes xenoantigens involved in porcine cellular xenograft rejection by mice', Transplantation, vol. 79, no. 12, pp. 1674-1682.
• Solomon, M, Kuziel, W & Simeonovic, C 2004, 'The contribution of chemokines and chemokine receptors to the rejection of fetal proislet allografts', Cell Transplantation, vol. 13, pp. 503-514.
• Solomon, M, Kuziel, W, Mann, D et al. 2003, 'The role of chemokines and their receptors in the rejection of pig islet tissue xenografts', Xenotransplantation, vol. 10, pp. 164-177.
• Simeonovic, C, Cordery, D, Van Leeuwen, B et al 2002, 'Host systemic and local nitric oxide levels do not correlate with rejection of pig proislet xenografts in mice', Xenotransplantation, vol. 9, pp. 169-182.
• Lidbury, B, Simeonovic, C, Maxwell, G et al 2000, 'Macrophage-induced muscle pathology results in morbidity and mortality for Ross River virus-infected mice', Journal of Infectious Diseases, vol. 181, no. 1, pp. 27-34.
• Paule, M, Ramshaw, I & Simeonovic, C 2000, 'Avipox virus vectors for gene delivery to fetal mouse and pig proislets', Transplantation Proceedings, vol. 32, no. 5, p. 1067.
• Paule, M, McColl, S & Simeonovic, C 2000, 'Murine chemokine gene expression in rejecting pig proislet xenografts', Transplantation Proceedings, vol. 32, no. 5, pp. 1062..
• Simeonovic, C, Townsend, M, Morris, C et al. 1999, 'Immune mechanisms associated with the rejection of fetal murine proislet allografts and pig proislet xenografts: comparison of intragraft cytokine mRNA profiles', Cell Transplantation, vol. 67, no. 7, pp. 963-971.
• Simeonovic, C 1999, 'Xenogeneic islet transplantation', Xenotransplantation, vol. 6, no. 1, pp. 1-5.
• Simeonovic, C, Townsend, M, Karupiah, G et al. 1999, 'Analysis of the Th1/Th2 paradigm in transplantation: interferon-gamma deficiency converts Th1-type proislet allograft rejection to a Th2-type xenograft-like response', Cell Transplantation, vol. 8, no. 4, pp. 365-373.

Projects and Grants

Grants information is drawn from ARIES. To add or update Projects or Grants information please contact your College Research Office.

• Impact of islet beta cell heparan sulfate in Type 2 diabetes (Primary Investigator)
• Mechanism of protection of islet beta cells from T1D by heparan sulfate (Primary Investigator)