Professor Klaus-Martin Schulte MD
MD, FRCS, FRACS
Professor and Chair of Transdisciplinary Health Research
ANU College of Health and Medicine
T:
+61451068567
Areas of expertise
- Surgery 110323
- Endocrinology 110306
- Medical Biochemistry And Metabolomics 3205
- Medical Physiology 3208
- Oncology And Carcinogenesis 3211
- Predictive And Prognostic Markers 321109
- Radiation Therapy 321110
Research interests
Indigenous Pharmacogenomics
Space Research including space hard sensor systems
The cellular biology of fusion oncoproteins in sarcoma
Endocrine cancer
Pheochromocytoma and paraganglioma
Parathyroid cancer
Biography
Born July 26th 1964, married, two children (aged 17 and 15)
CURRENT POSITIONS
2024 – Professor & Chair of Transdisciplinary Health Research, Australian National University
2010 – Professor extraordinarius of Surgery, University of Düsseldorf, Germany (UKD)
2004 - Consultant Endocrine Surgeon at King’s College Hospital (KCH), London (part-time since 2014)
2004 - Lead Clinician Endocrine Surgery KCH
FORMER POSITIONS
2012 - 2017 Honorary Reader of Endocrine Surgery at King’s College London
2007 - 2012 Honorary Senior Lecturer in Surgery at King's College London
2007 - 2012 Lead Clinician for Emergency General and Major Trauma Surgery, KCH, Level I Trauma Centre
2001 - 2003 Programm Director of Surgery (6000 surgeries per annum)
1998 - 2003 Head of the Laboratory of Surgery UKD and Supervisor of Gene Technology University Clinics Duesseldorf, Germany
1998 - 2000 Senior Research Fellow of the German National Research Foundation DFG
1998 - 2004 Principal Investigator in 5 projects with category 1 funding
TERTIARY EDUCATION
1990 Harvard Medical School
1989 Baylor College Houston
1985-1987 University of Paris, College de France
1983-1989 University of Essen
1990 ECFMG part 1 & 2
GRANTS & AWARDS
2004 – date annual recipient of clinical excellence awards, KCH
2002 von Langenbeck Award of the German Society of Surgery
1999 Dr. Günther Wille Award for research on Adrenal tumorigenesis
1998 - 2000 Research Fellowship (Habilitationsstipendium) German National Research Foundation DFG
1998 Oberdisse Award of the NRW Society of Endocrinology for research on "Thyroid growth regulation"
1991 - 1995 Scholarship of the Alfried-Krupp-von-Bohlen-und-Halbach Foundation
1985 - 1990 Scholarship German National Scholarship Foundation
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Publications
- Galata', G, Alexandrou, K, Talat, N et al. 2023, 'Defining the feasibility of same day adrenalectomy - A prospective matched cohort study', Surgery Open Science, vol. 14, pp. 75-80.
- Schulte KM, Galata', G & Talat, N 2022, 'Mediastinal Parathyroid Cancer', Cancers, vol. 14, no. 23, pp. 1-15.
- Schulte KM, Talat, N & Galata', G 2022, 'Margin Free Resection Achieves Excellent Long Term Outcomes in Parathyroid Cancer', Cancers, vol. 15, no. 1, pp. 1-18.
- van Loon, L, Steins, A, Schulte KM et al. 2022, 'Computational modeling of orthostatic intolerance for travel to Mars', npj Microgravity, vol. 8, no. 1, pp. 1-10.
- Carroll, C, Andrew, E, Malik, L et al. 2021, 'Simple and effective bacterial-based intratumoral cancer immunotherapy', Journal for ImmunoTherapy of Cancer, vol. 9, no. 9.
- Ebrahimi, A, Gupta, R, Luk, P et al. 2020, 'Number of nodal metastases and the American Joint Committee on cancer staging of head and neck cutaneous squamous cell carcinoma: A multicenter study', Oral Oncology, vol. 111, pp. 1-7.
- Bornstein, S, Voit-Bak, K, Schmidt, D et al. 2020, 'Is There a Role for Environmental and Metabolic Factors Predisposing to Severe COVID-19?', Hormone and Metabolic Research, vol. 52, no. 7, pp. 540-546.
- Fang, C, Konstantatou, E, Mulholland, N et al. 2018, 'A retrospective review of the role of B-mode and color Doppler ultrasonography in the investigation of primary hyperparathyroidism: Features that differentiate benign from malignant lesions', Ultrasound, vol. 26, no. 2, pp. 110-117.
- Graessler, J, Mehnert, C, Schulte KM et al. 2018, 'Urinary Lipidomics: Evidence for multiple sources and sexual dimorphism in healthy individuals', Pharmacogenomics Journal, vol. 18, no. 2, pp. 331-339.
- Taylor, D, Ghataore, L, Couchman, L et al. 2017, 'A 13-Steroid Serum Panel Based on LC-MS/MS: Use in Detection of Adrenocortical Carcinoma', Clinical Chemistry, vol. 63, no. 12, pp. 1836-1846pp.
- Johar, A, Sarmiento-Monroy, J, Rojas-Villarraga, A et al. 2016, 'Definition of mutations in polyautoimmunity', Journal of Autoimmunity, vol. 72, pp. 65-72.
- Lunevicius, R, Lewis, D, Ward, R et al. 2014, 'Penetrating injury to the buttock: an update', Techniques in Coloproctology, vol. 18, no. 11, pp. 981-992.
- Perna, V, Taylor, N, Dworakowska, D et al. 2014, 'Adrenocortical adenomas with regression and myelolipomatous changes: urinary steroid profiling supports a distinctive benign neoplasm', Clinical Endocrinology, vol. 81, no. 3, pp. 343-349.
- Chatzigeorgiou, A, Seijkens, T, Zarzycka, B et al. 2014, 'Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance', PNAS - Proceedings of the National Academy of Sciences of the United States of America, vol. 111, no. 7, pp. 2686-2691.
- Whitelaw, B, Prague, J, Mustafa, O et al. 2014, 'Phaeochromcytoma crisis', Clinical Endocrinology, vol. 80, no. 1, pp. 13-22.
- Al Bunni, F, Deganello, A, Sellars, M et al. 2014, 'Contrast-enhanced ultrasound (CEUS) appearances of an adrenal phaeochromocytoma in a child with Von Hippel-Lindau disease', Journal of Ultrasound, vol. 17, no. 4, pp. 307-311.
- Ban, R, Kamvissi, V, Schulte KM et al. 2014, 'Lipidomic Profiling at the Interface of Metabolic Surgery and Cardiovascular Disease', Current Atherosclerosis Reports, vol. 16, no. 11, pp. 455-455.
- Chicklore, S, Schulte KM, Talat, N et al. 2014, 'F-18-FDG PET Rarely Provides Additional Information to C-11-Methionine PET Imaging in Hyperparathyroidism', Clinical Nuclear Medicine, vol. 39, no. 3, pp. 237-242.
- Diggins, B, Diaz-Cano, S & Schulte KM 2014, 'Campylobacter jejuni as a cause of acute infectious thyroiditis, on a background of SLE-related end stage renal failure and CMV viraemia: A case report and review of the literature', Journal of Vaccines & Vaccination, vol. 5, no. 3.
- Galata, G & Schulte KM 2014, 'Management of the thyroid nodule', Surgery, vol. 32, no. 10, pp. 531-536.
- Komninos, G, Schulte KM & Galata', G 2014, 'Giant recurrent intrathoracic goitre treated by clamshell thoracotomy and reverse sternotomy', BMJ Case Reports, vol. 2014, no. -, pp. 1-4.
- Schulte KM, Talat, N, Galata, G et al. 2014, 'Genetics and the Clinical Approach to Paragangliomas', Hormone and Metabolic Research, vol. 46, no. 13, pp. 964-973.
- Schulte KM, Talat, N, Galata, G et al. 2014, 'Oncologic Resection Achieving R0 Margins Improves Disease-Free Survival in Parathyroid Cancer', Annals of Surgical Oncology, vol. 21, no. 6, pp. 1891-1897.
- Samji, K, Crown, A, Buxton-Thomas, M et al. 2012, 'Necessity for long-term follow-up of patients with head and neck paraganglioma and mutation in the succinate dehydrogenase genes: An index case report and literature review', Endocrine Practice, vol. 18, no. 5, pp. e130-4.
- Ghataore, L, Chakraborti, I, Aylwin, S et al. 2012, 'Effects of mitotane treatment on human steroid metabolism: implications for patient management', Endocrine Connections, vol. 1, no. 1, pp. 37-47.
- Harris, R, Olding, C, Lacey, C et al. 2012, 'Changing incidence and management of penetrating neck injuries in the South East London trauma centre', Annals of the Royal College of Surgeons of England, vol. 94, no. 4, pp. 240-244.
- Mulla, M, Knoefel, W, Gilbert, J et al. 2012, 'Lateral cervical lymph node metastases in papillary thyroid cancer: A systematic review of imaging-guided and prophylactic removal of the lateral compartment', Clinical Endocrinology, vol. 77, no. 1, pp. 126-131.
- Mulla, M & Schulte KM 2012, 'Central cervical lymph node metastases in papillary thyroid cancer: A systematic review of imaging-guided and prophylactic removal of the central compartment', Clinical Endocrinology, vol. 76, no. 1, pp. 131-136.
- Mulla, M & Schulte KM 2012, 'Papillary Thyroid Cancer: The Problem of Regional Lymph Node Metastases', in Kreuger & Trommler (ed.), Thyroid Cancer: Diagnosis, Treatment and Prognosis, Nova Science Publishers Inc, US, pp. 87-100pp.
- Mulla, M & Schulte KM 2012, 'Terminology inaccuracies in the interpretation of imaging results in detection of cervical lymph node metastases in papillary thyroid cancer', Endocrine Connections, vol. 1, no. 2, pp. 78 - 86.
- Schulte KM & Roher, H 2012, 'History of thyroid and parathyroid surgery', in Gregory W Randolph (ed.), Surgery of the Thyroid and Parathyroid Glands, Elsevier, US, pp. 1-15.
- Schulte KM & Talat, N 2012, 'Diagnosis and management of parathyroid cancer', Nature Reviews. Endocrinology, vol. 8, no. 10, pp. 612-622.
- Schulte KM 2012, 'The accuracy of ultrasonography in the preoperative diagnosis of cervical lymph node (LN) metastasis in patients with papillary thyroid carcinoma: A meta-analysis', European Journal of Radiology, vol. 81, no. 8, pp. 1965-1965.
- Schulte KM, Gill, A, Barczynski, M et al. 2012, 'Classification of parathyroid cancer', Annals of Surgical Oncology, vol. 19, no. 8, pp. 2620-2628.
- Talat, N, Belgaumkar, A & Schulte KM 2012, 'Surgery in Castleman's Disease A Systematic Review of 404 Published Cases', Annals of Surgery, vol. 255, no. 4, pp. 677-684.
- Schulte MD, K, Sinha, P, Talat, N et al. 2011, 'RETROPERITONEAL UNICENTRIC CASTLEMAN S DISEASE WITH MULTIPLE LYMPH NODE INVOLVEMENT', BMJ Case Reports, vol. 2011, pp. 4pp.
- Sidhu, P, Talat, N, Patel, P et al. 2011, 'Ultrasound features of malignancy in the preoperative diagnosis of parathyroid cancer: A retrospective analysis of parathyroid tumours larger than 15 mm', European Radiology, vol. 21, no. 9, pp. 1865-1873.
- Dixon, L, Diaz-Cano, S & Schulte KM 2011, 'Psittacosis infection and tracheobronchomalacia in a patient undergoing thyroidectomy', BMJ Case Reports, vol. 2011, pp. -.
- Galata, G & Schulte KM 2011, 'Management of the thyroid nodule', Surgery, vol. 29, no. 9, pp. 434-439.
- Lunevicius, R & Schulte KM 2011, 'Analytical review of 664 cases of penetrating buttock trauma', World Journal of Emergency Surgery, vol. 6, no. 33.
- Schulte KM 2011, 'Chirurgische Anatomie der Schilddrüse (Surgical anatomy of the thyroid)', in J R Siewert, M Rothmund & V Schumpelick (ed.), Praxis der Viszeralchirurgie: Gastroenterologische Chirurgie (Practice of visceral surgery: Gastroenterological Surgery), Springer Berlin Heidelberg, New York, USA.
- Schulte KM 2011, 'Operative Therapie bei Thyroiditis (Surgery in thyroiditis)', in J R Siewert, M Rothmund & V Schumpelick (ed.), Praxis der Viszeralchirurgie: Gastroenterologische Chirurgie (Practice of visceral surgery: Gastroenterological Surgery), Springer Berlin Heidelberg, New York, USA.
- Talat, N & Schulte KM 2011, 'Castleman's disease: Systematic analysis of 416 patients from the literature', Oncologist, vol. 16, no. 9, pp. 1316-1324.
- Talat, N, Diaz-Cano, S & Schulte KM 2011, 'Inflammatory diseases of the parathyroid gland', Histopathology, vol. 59, no. 5, pp. 897-908.
- Karamchandani, D, Arias-Amaya, R, Donaldson, N et al. 2010, 'Thyroid cancer and renal transplantation: A meta-analysis', Endocrine-Related Cancer, vol. 17, no. 1, pp. 159-167.
- Simms, J, El-Sakka, K, Valenti, D et al. 2010, 'Small bowel obstruction due to herniation into an extra-anatomical arterial bypass tunnel: A first case report', Annals of the Royal College of Surgeons of England, vol. 92, no. 2, pp. 1-3.
- Schulte KM & Talat, N 2010, 'Castleman's disease-a two compartment model of HHV8 infection', Nature Reviews Clinical Oncology, vol. 7, no. 9, pp. 533-543.
- Schulte KM, Machens, A, Fugazzola, L et al. 2010, 'The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A', Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 9, pp. E92-E97.
- Schulte KM, Talat, N, Miell, J et al. 2010, 'Lymph node involvement and surgical approach in parathyroid cancer', World Journal of Surgery, vol. 34, no. 11, pp. 2611-2620.
- Talat, N & Schulte KM 2010, 'Clinical presentation, staging and long-term evolution of parathyroid cancer', Annals of Surgical Oncology, vol. 17, no. 8, pp. 2156-2174.
- Raffel, A, Cupisti, K, Dotzenrath, B et al. 2004, 'Economic restraints shorten the length of hospital stay: thyroid operation As a model case', European Journal of Endocrinology, vol. 75, no. 5, pp. 837-840.
- Raffel, A, Cupisti, K, Krausch, M et al. 2004, 'Incidentally found medullary thyroid cancer - treatment rationale for small tumours', World Journal of Surgery, vol. 28, pp. 397-401.
- Raffel, A, Engers, R, Cupisti, K et al. 2004, 'Multiple neuroendocrine tumors of the pancreas associated with pancreas divisum.', European Journal of Endocrinology, vol. 150, pp. 837-840.
- Laun, R, Schroeder, O, Schoppnies, M et al. 2003, 'Transforming growth factor-beta 1 and major trauma: Time-dependent association with hepatic and renal insufficiency.', Shock, vol. 19, no. 1, pp. 16-23.
- SIDHU, S, Marsh, D, THEODOSOPOULOS, G et al. 2002, 'Comparative genomic hybridization analysis of adrenocortical tumors', Journal of Clinical Endocrinology and Metabolism, vol. 87, no. 7, pp. 3467-2474.
- Schulte, C, GOEBELL, H, Roher, H et al. 2001, 'C-509T polymorphism in the TGFB1 gene promoter: impact on Crohn's disease susceptibility and clinical course?', Immunogenetics, vol. 53, pp. 178-182.
- Laun, R, Rapsch, B, Abel, W et al. 2001, 'The determination of ketone bodies: preanalytical, analytical and physiological considerations.', Clinical and Experimental Medicine, vol. 1, pp. 201-209.
- Schulte, C, GOEBELL, H, Roher, H et al. 2001, 'Genetic determinants of IL-6 expression levels do not influence bone loss in inflammatory bowel disease', Digestive Diseases and Sciences, vol. 46, no. 11, pp. 2521-2528.
- Schulte KM, Beyer, A, K¨OHRER, K et al. 2001, 'Lysophosphatidic acid, a novel lipid growth factor for human thyroid cells: Over-expression of the high-affinity receptor EDG4 in differentiated thyroid cancer', International Journal of Cancer, vol. 92, pp. 249-256.
- Schulte KM, Jonas, C, Krebs, R et al. 2001, 'Activin A and activin receptors in thyroid cancer', Thyroid, vol. 11, no. 1, pp. 3-14.
- Schulte, KM, Roher, H 2001, 'Complications in the surgery of benign thyroid disease', Acta Medica Austriaca, vol. 33, no. 4, pp. 164-172.
- Schulte, C, DIGNASS, A, GOEBELL, H et al. 2000, 'Genetic factors determine extent of bone loss in inflammatory bowel disease', Gastroenterology, vol. 119, pp. 909-920.
- Schulte KM, Mengel, M, Heinze, M et al. 2000, 'Complete sequencing and messenger ribonucleic acid expression analysis of the MEN I gene in adrenal cancer', Journal of Clinical Endocrinology and Metabolism, vol. 85, pp. 441-448.
- Goretzki, P, Dotzenrath, C, Witte, J et al. 1999, 'Struma maligna', Der Onkologe, vol. 5, pp. 104-114.
- Schulte KM & Roeher, H 1999, 'Medico-legal aspects of thyroid surgery', Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, vol. 70, pp. 1131-1138.
- Schulte KM, Heinze, M, Mengel, M et al. 1999, 'MEN I gene mutations in sporadic adrenal adenomas', Human Genetics, vol. 105, pp. 603-610.
- STURM, A, SUDERMANN, T, Schulte KM et al. 1999, 'Modulation of intestinal epithelial wound healing in vitro and in vivo by lysophosphatidic acid', Gastroenterology, vol. 117, pp. 368-377.
- STURM, A, BECKER, A, Schulte MD, K et al. 1998, 'Effect of Prophylactic Ganciclovir on Cytomegalovirus-Infection in Renal-Transplant Recipients', Annals of the New York Academy of Sciences, vol. 859, pp. 223-226.
Projects and Grants
Grants information is drawn from ARIES. To add or update Projects or Grants information please contact your College Research Office.
- iLAuNCH - Manufacturing wearable-based health solutions for space medicine (Primary Investigator)
- Advancing health equity for Indigenous Australians through pharmacogenomics: building an end-to-end discovery pipeline (Primary Investigator)
- NHMRC Small Equipment Grant 2022 - Luna FX7 Automated Cell Counter - Link to ARIES 41237 (Secondary Investigator)
- iLAuNCH Hub (Secondary Investigator)
- NHMRC Equipment Grant 2021: ACDT Equipment - Linked to ARIES ID 39296 (Secondary Investigator)
- The nucleolar stress response at the centre of the malignant phenotype (Secondary Investigator)
