Dr Jason Potas

Lecturer (Physiology), Team Leader (Neural Control Systems Laboratory, JCSMR)
ANU College of Health and Medicine

Research interests

Humans have a sophisticated somatosensory system (system of body sensors) which performs a variety of tasks we take for granted. Not only does it provide our motor system with feedback that enables fine motor control, but it also connects our brains to the outside world by providing us with the capacity to explore our environment as well as enjoy a physical connection with others.

While there have been recent outstanding advancements in motor prosthetics which can read brain signals and translate these into complex movement of a robotic arm, the loss of somatosensation limits the success of these motor prostheses. We are yet to work out how to close the loop with sensory feedback which is necessary to inform the brain of the position and textural experiences which drive our motor system to react appropriately. However, even with motor function, those who lose somatosensation (for example due to spinal cord injury or nerve damage) become disconnected from others including loved ones. Imagine what it must be like to shake someone’s hand, or picking up a small child, after your hand is replaced with a mechanical device; not only would you have poor grip, but you would miss out on the experience of the warmth and softness of human contact.

The focus of our research is to “close the loop” on sensorimotor control. We use a combination of electrophysiology, signal processing and machine learning in small animal models to discover how sensory information is coded in different parts of the central nervous system. We are looking at certain brain regions for the potential to replaced lost sensory information with electrical inputs from a prosthetic device (neuroprosthesis).

Our brain region of interest is the dorsal column nuclei (DCN), where somatosensory information from the body is “summarised” before it is sent to higher brain regions for further processing. By stimulating the body and recording multiple electrical signatures in the DCN, we have been able to extract information and use machine learning to inform us of: i) the location, and ii) the quality of a sensory event experienced on the body. By reading the DCN, we can already successfully discriminate between various somatosensory modalities such as different tactile stimuli as well as changes in limb position.


Dr Potas is currently a visiting fellow at ANU in the Department of Neuroscience at the John Curtin School of Medical Research.

Dr Potas commenced his scientific career at The University of Sydney, examining how different sensory (somatic and visceral) information affects blood pressure, by studying the spinal and brainstem functional and anatomical connections to autonomic control centres, and how the functional output pathways of these control centres affect blood pressure. During his first post-doc (Charité, Berlin), Dr Potas studied the cellular responses to cerebral ischemia. In his second post-doc (UNSW, Sydney), he investigated the cellular responses and the role of the immune system in reducing dysfunctional outcomes after spinal cord injury. In his third post-doc (UFRJ, Brazil) Dr Potas examined the electrophysiological properties of regenerating nervous tissues following peripheral nerve and spinal cord injury, and devised new injury models and evaluation techniques that allow the assessment of nervous functional integrity. Whilst in Brazil, he also devised a computational technique that allowed him to automatically evaluate peripheral nerve function, as well as techniques for differentiating nervous fibre types based on their electro-morphological characteristics. After a three year career break working as an applications scientist in industry, Dr Potas joined the Australian National University Medical School in 2010 at the John Curtin School of Medical Research where he contributed to teaching physiology and neuroscience and leads a research team studying sensory processing and pain.

Available student projects

Bionic touch: We are investigating the potential for the DCN as a somatosensory neuroprosthetic target. This project decodes sensory signals in the DCN in response to peripheral stimuli to predict the location and quality of sensory input. We will also stimulate the DCN to “recreate” the same electrical signatures evoked by natural stimuli.

DCN activity mapping: DCN activity is not symmetrically mapped across the surface of the brainstem. This project investigates the asymmetry of sensory representation in the context of handedness.

Spinal cord pre-processing of somatosensation: Sensory information may be significantly modified between the periphery and the DCN. This project focuses on the influence the spinal cord has on modulating ascending sensory inputs to the DCN.

Red light therapy in neuronal injury: Another interest of our group is how the somatosensory and motor systems are affected by injury. This project investigates the use of red light therapy for treating the nervous system in response to injury.


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Updated:  14 July 2024 / Responsible Officer:  Director (Research Services Division) / Page Contact:  Researchers