Professor Lewis Mander

ANU College of Science

E: lew.mander@anu.edu.au

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Areas of expertise

Natural Products Chemistry 030502
Biologically Active Molecules 030401
Gene Expression (Incl. Microarray And Other Genome Wide Approaches) 060405
Biography 210304
Plant Physiology 060705
Plant Systematics And Taxonomy 060310
Structural Chemistry And Spectroscopy 030606
Molecular Evolution 060409
Plant Cell And Molecular Biology 060702
Separation Science 030108
Organic Chemical Synthesis 030503
Physical Organic Chemistry 030505
Medicinal And Biomolecular Chemistry 0304
Organic Chemistry 0305

Publications

McLachlan, M, O'Connor, P, Fairweather, K et al. 2010, 'Total Synthesis of the Galbulimima Alkaloid (Â±)-GB 13', Australian Journal of Chemistry, vol. 63, no. 5, pp. 742-760.
Hayashi, K, Horie, K, Hiwatashi, Y et al 2010, 'Endogenous diterpenes derived from ent-kaurene, a common gibberellin precursor, regulate protonema differentiation of the moss Physcomitrella patens', Plant Physiology, vol. 153, no. 3, pp. 1085-1097.
Ayele, B, Magnus, V, Mihaljevic, S et al 2010, 'Endogenous gibberellin profile during Christmas rose (Helleborus niger L.) flower and fruit development', Journal of Plant Growth Regulation, vol. 29, no. 2, pp. 194-209.
Mander, L, ed., 2010, Modern Methods in Natural Products Chemistry - Volume 9 of Comprehensive Natural Products Chemistry II: Chemistry and Biology, Elsevier, Oxford.
Mander, L & Liu, H, eds, 2010, Comprehensive Natural Products Chemistry II: Chemistry and Biology, Elsevier, Oxford.
O'Connor, P, Del Signore, G, McLachlan, M et al 2010, 'Approaches to the Synthesis of the Galbulimima Alkaloid Himandrine', Australian Journal of Chemistry, vol. 63, no. 10, pp. 1477-1491.
Fairweather, K, Mander, L & Pharis, R 2010, Expeditious Synthesis of Gibberllin A₅ and Esters Thereof, WO 2010/032136 A1, Other International.
Mander, L, Willis, A, Herlt, A et al 2009, 'The structures of three new Galbulimima alkaloids', Tetrahedron Letters, vol. 50, no. 50, pp. 7089-7092.
King, R, Mander, L, Asp, T et al 2008, 'Selective deactivation of gibberellins below the shoot apex is critical to flowering but not to stem elongation of Lolium', Molecular Plant, vol. 1, no. 2, pp. 295-307.
Chandler, P, Harding, C, Ashton, A et al 2008, 'Characterization of gibberellin receptor mutants of barley (Hordeum vulgare L.)', Molecular Plant, vol. 1, no. 2, pp. 285-294.
Fairweather, K, Crabtree, S & Mander, L 2008, 'A formal total synthesis of the marine diterpenoid, diisocyanoadocaine', in Michael Harmata (ed.), Strategies and Tactics in Organic Synthesis, Elsevier, London, UK, pp. 35-58.
Hutt, O & Mander, L 2008, 'Formation of the C6-N-C20 bridge for entry into the hetisane skeleton', Australian Journal of Chemistry, vol. 61, no. 3, pp. 204-208.
Beck, E, Chandler, P, Thomson, R et al. 2008, 'Synthesis and bioactivity of the gibberellin, 18 hydroxy-GA₁ (GA₁₃₂)', Organic and Biomolecular Chemistry, vol. 6, no. 8, pp. 1416-1424.
Le, T, Mander, L, Koshioka, M et al. 2008, 'Confirmation of structure and synthesis of three new 11Î²-OH C₂₀ gibberellins from loquat fruit', Tetrahedron, vol. 64, no. 21, pp. 4835-4851.
O'Sullivan, T, Zhang, H & Mander, L 2007, 'Model studies toward the synthesis of the bioactive diterpenoid, harringtonolide', Organic and Biomolecular Chemistry, vol. 5, no. 16, pp. 2627-2635.
Varbanova, M, Yamaguchi, S, Yang, Y et al 2007, 'Methylation of gibberellins by Arabidopsis GAMT1 and GAMT2', The Plant Cell, vol. 19, no. 1, pp. 32-45.
Hutt, O & Mander, L 2007, 'Studies toward the total synthesis of nominine', Journal of Organic Chemistry, vol. 72, no. 26, pp. 10130-10140.
Willis, A, O'Connor, P, Taylor, W et al 2006, 'The absolute stereochemistry of the Galbulimima alkaloids', Australian Journal of Chemistry, vol. 59, no. 9, pp. 629-632.
Fukuda, N, Kondo, M, Nishimura, S et al 2006, 'The role of phytohormones in flowering and bolting of spinach (Spinacia oleracea L.) under mid-night lighting', Acta Horticulturae, vol. 711, pp. 247-253.
Crow, J, Thomson, R & Mander, L 2006, 'Synthesis and confirmation of structure for the giberellin GA₁₃₁ (18-hydroxy-GA₄)', Organic and Biomolecular Chemistry, vol. 4, no. 13, pp. 2532-2544.
Fairweather, K & Mander, L 2006, 'A formal total synthesis of the marine diterpenoid diisocyanoadociane', Organic Letters, vol. 8, no. 15, pp. 3395-3398.
Zhu, Y, Nomura, T, Xu, Y et al 2006, 'ELONGATED UPPERMOST INTERNODE encodes a cytochrome P450 monooxygenase that epoxidizes gibberellins in a novel deactivation reaction in rice', The Plant Cell, vol. 18, no. 2, pp. 442-456.
Nakagawa, H, Jiang, C, Sakakibara, H et al 2005, 'Overexpression of a petunia zinc-finger gene alters cytokinin metabolism and plant forms', The Plant Journal, vol. 41, no. 4, pp. 512-523.
Mander, L & Thomson, R 2005, 'Total synthesis of sordaricin', Journal of Organic Chemistry, vol. 70, no. 5, pp. 1654-1670.
Williams, C, Mander, L, Bernhardt, P et al 2005, 'Investigating direct routes to an advanced intermediate for the synthesis of C-20 diterpene alkaloids', Tetrahedron, vol. 61, no. 15, pp. 3759-3769.
Hutt, O, Mander, L & Willis, A 2005, 'Ring fragmentation processes resulting from acid catalysed diazo ketone cyclisations', Tetrahedron Letters, vol. 46, no. 27, pp. 4569-4572.
Liu, J, Mander, L & Koshioka, M 2004, 'Methodology for the synthesis of 11,13-dihydroxy gibberellins', ARKIVOC, vol. 2004, no. x, pp. 68-79.
Herlt, A, Mander, L, Rombang, W et al 2004, 'Alkaloids from marine organisms. Part 8: Isolation of bisdemethylaaptamine and bisdemethylaaptamine-9-O-sulfate from an Indonesian Aaptos sp. marine sponge', Tetrahedron, vol. 60, no. 29, pp. 6101-6104.
Hisamatsu, T, Koshioka, M & Mander, L 2004, 'Regulation of gibberellin biosynthesis and stem elongation by low temperature in Eustoma grandiflorum', Journal of Horticultural Science and Biotechnology, vol. 79, no. 3, pp. 354-359.
Beck, E, Twitchin, B & Mander, L 2004, 'Radio labelling of the gibberellin plant growth inhibitor 16,17-dihydro-GA₅', Canadian Journal of Chemistry, vol. 82, no. 2, pp. 293-300.
King, R, Junttila, O, Mander, L et al. 2004, 'Gibberellin structure and function: Biological activity and competitive inhibition of gibberellin 2- and 3-oxidases', Physiologia Plantarum, vol. 120, no. 2, pp. 287-297.
O'Connor, P, Mander, L & McLachlan, M 2004, 'Synthesis of the himandrine skeleton', Organic Letters, vol. 6, no. 5, pp. 703-706.
Williams, C & Mander, L 2004, 'Guaiacol transprotection: replacement of the phenoxy isopropyl protecting function by acetyl', Tetrahedron Letters, vol. 45, no. 4, pp. 667-669.
Ubukawa, M, Fukuda, N, Oyama-Okubo, N et al 2004, 'Effect of light source and quality on endogenous gibberellin level and GA₃ response of petunia (Petunia x hybrida Vilm)', Journal of the Japanese Society for Horticultural Science, vol. 73, no. 5, pp. 441-446.
Mander, L 2003, 'Twenty years of gibberellin research', Natural Product Reports, vol. 20, no. 1, pp. 49-69.
Mander, L & Thomson, R 2003, 'Total Synthesis of Sordaricin', Organic Letters, vol. 5, no. 8, pp. 1321-1324.
Leitch, S, Blake, P & Mander, L 2003, 'Synthesis and structure determination of three new 12Î²-hydroxy C₂₀ gibberellins (GA₁₂₇, GA₁₂₈ and GA₁₂₉)', ARKIVOC, vol. n/a, no. 7, pp. 145-160.
Buttle, L, Morris, J & Mander, L 2003, 'Further investigations into the preparation and [4+2] cycloaddition reactions of vinyl norcaradiene derivatives', ARKIVOC, vol. n/a, no. 8, pp. 118-134.
Williams, C & Mander, L 2003, 'Bridgehead Arylation: A Direct Route to Advanced Intermediates for the Synthesis of C-20 Diterpene Alkaloids', Organic Letters, vol. 5, no. 19, pp. 3499-3502.
King, R, Evans, L, Mander, L et al 2003, 'Synthesis of gibberellin GA₆ and its role in flowering of Lolium temulentum', Phytochemistry, vol. 62, no. 1, pp. 77-82.
Mander, L & O'Sullivan, T 2003, 'An exploration of the potential of [4+2] cycloadditions of Î±-pyrones with indenones for the synthesis of the norditerpenoid tropone, harringtonolide', Synlett, vol. n/a, no. 9, pp. 1367-1369.
Adamson, G & Mander, L 2003, 'Conversion of Gibberellic Acid into the B-Ring seco-Kaurenoid, Longirabdolactone', Australian Journal of Chemistry, vol. 56, no. 8, pp. 805-809.
Williams, C, Mander, L & Bernhardt, P 2003, '1-Ethynyl-2-isopropoxy-3-methoxybenzene', Acta Crystallographica Section E: Structure Reports Online, vol. E59, no. 4, pp. o561-o563.
Mander, L & McLachlan, M 2003, 'The Total Synthesis of the Galbulimima Alkaloid GB 13', Journal of the American Chemical Society, vol. 125, no. 9, pp. 2400-2401.
Stokes, T, Mander, L, Croker, S et al 2003, '3Î²,13-Dihydroxylated C₂₀ gibberellins from inflorescences of Rumex acetosa L.', Phytochemistry, vol. 62, no. 2, pp. 165-174.
Mander, L & Williams, C 2003, 'Oxidative degradation of benzene rings', Tetrahedron, vol. 59, no. 8, pp. 1105-1136.
Mander, L 2003, 'Charles William Shoppee 1904-1994', Historical Records of Australian Science, vol. 14, pp. 509-528.
Mander, L 2003, 'Charles William Shoppee', Biographical Memoirs of Fellows of the Royal Society, vol. 49, pp. 495-507.
Jacobsen, J, Pearce, D, Poole, A et al 2002, 'Abscisic acid, phaseic acid and gibberellin contents associated with dormancy and germination in barley', Physiologia Plantarum, vol. 115, no. 3, pp. 428-441.
Herlt, A, Mander, L, Pongoh, E et al 2002, 'Two Major Saponins from Seeds of Barringtonia asiatica: Putative Antifeedants toward Epilachna sp. Larvae', Journal of Natural Products, vol. 65, no. 2, pp. 115-120.
Pearce, D, Hutt, O, Rood, S et al 2002, 'Gibberellins in shoots and developing capsules of Populus species', Phytochemistry, vol. 59, no. 6, pp. 679-687.
Liu, J & Mander, L 2002, 'Attempt to build 13-hydroxy-9,15-cyclo GA skeletons', Chinese Chemical Letters, vol. 13, no. 12, pp. 1152-1153.
Zhang, H, Wynne, G & Mander, L 2001, 'Synthesis of ent-9&alpha,15&alpha-cyclokaurene from grandiflorenic acid', ARKIVOC, vol. 2, no. 10, pp. ms Govi5.
Williams, C & Mander, L 2001, 'Chromatography with silver nitrate', Tetrahedron, vol. 57, no. 3, pp. 425-447.
Kurumatani, M, Yagi, K, Murata, T et al 2001, 'Isolation and identification of antheridiogens in the ferns, Lygodium microphyllum and Lygodium reticulatum', Bioscience Biotechnology and Biochemistry, vol. 65, no. 10, pp. 2311-2314.
Chang, S, Chen, W, Koshioka, M et al 2001, 'Gibberellins in relation to flowering in Polianthes tuberosa', Physiologia Plantarum, vol. 112, no. 3, pp. 429-432.
Su, W, Chen, W, Koshioka, M et al 2001, 'Changes in gibberellin levels in the flowering shoot of Phalaenopsis hybrida under high temperature conditions when flower development is blocked', Plant Physiology and Biochemistry, vol. 39, no. 1, pp. 45-50.
Nakayama, M, Koshioka, M, Matsui, H et al 2001, 'Endogenous gibberellins in immature seeds of Prunus persica L.: identification of GA₁₁₈, GA₁₁₉, GA₁₂₀, GA₁₂₁, GA₁₂₂ and GA₁₂₆', Phytochemistry, vol. 57, no. 5, pp. 749-758.
Niki, T, Nishijima, T, Nakayama, M et al 2001, 'Production of dwarf lettuce by overexpressing a pumpkin gibberellin 20-oxidase gene', Plant Physiology, vol. 126, no. 3, pp. 965-972.
Mander, L & Thomson, R 2000, 'C-18 Hydroxylation of gibberellins', Journal of the Chemical Society, Perkin Transactions 1, vol. 17, pp. 2893-2894.
Hisamatsu, T, Koshioka, M, Kubota, S et al 2000, 'The role of gibberellin biosynthesis in the control of growth and flowering in Matthiola incana', Physiologia Plantarum, vol. 109, no. 1, pp. 97-105.
Hisamatsu, T, Koshioka, M, Kubota, S et al 2000, 'FLOWER PROMOTION OF MATTHIOLA INCANA (L.) R. BR. BY GIBBERELLIN BIOSYNTHESIS INHIBITORY ACYLCYCLOHEXANEDIONES', 25th International Horticultural Congress, ed. Bodson, Professor Dr M.; Verhoyen, Professor Dr M.N.J., International Society for Horticultural Science, Leuven, Belgium, pp. 33-38.
Blake, P, Browning, G, Benjamin, L et al. 2000, 'Gibberellins in seedlings and flowering trees of Prunus avium L.', Phytochemistry, vol. 53, no. 4, pp. 519-528.
Blake, P, Taylor, D, Crisp, C et al 2000, 'Identification of endogenous gibberellins in strawberry, including the novel gibberellins GA123, GA124 and GA125', Phytochemistry, vol. 55, no. 8, pp. 887-890.
Frey, B, Wells, A, Roden, F et al 2000, 'Total Synthesis of the Pentacyclic Diterpenoid Tropone Hainanolidol', Australian Journal of Chemistry, vol. 53, no. 10, pp. 819-830.
Rogers, D, Frey, B, Roden, F et al 1999, 'Exploratory studies on the synthesis of the unusual diterpenoid tropone harringtonolide', Australian Journal of Chemistry, vol. 52, pp. 1093-1108.
Rademacher, W, Pharis, R & Mander, L 1999, 'Agricultural use of new GA derivatives', Japanese Journal of Crop Science, vol. 68, pp. 362-367.
Benjamin, L, Adamson, G & Mander, L 1999, 'Expansion of ring B in the gibberellins: entry to the rabdosia family of kaurenoids', Heterocycles, vol. 50, pp. 365-375.
Hisamatsu, T, Koshioka, M, Oyama, N et al. 1999, 'The relationship between endogenous gibberellins and rosetting in Eustoma grandiflorum', Journal of the Japanese Society for Horticultural Science, vol. 68, pp. 527?533.
Koshioka, M, Roh, M, Nakayama, M et al 1999, 'Identification of endogenous gibberellins in inflorescence of Ornithogalum thyrsoides', Journal of the Japanese Society for Horticultural Science, vol. 68, pp. 1158?1160.

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Updated: 19 April 2024 / Responsible Officer: Director (Research Services Division) / Page Contact: Researchers