Dr Nicolò Malagutti

BEng-Biomed (Milan), MBiomedEng (Milan), PhD (ANU)
ANU College of Engineering, Computing and Cybernetics

Areas of expertise

  • Biomedical Engineering 0903
  • Biomechanical Engineering 090302
  • Biomedical Instrumentation 090303
  • Medical Devices 090304
  • Circuits And Systems 090601
  • Systems Physiology 111603
  • Italian Language 200309

Research interests

  • Modelling and control of physiological systems.
  • Sleep medicine 
  • Technology-assisted delivery of medicines. 
  • Medical applications of engineering. Medical devices.
  • Engineering Education


Nicolo holds a Bachelor and Master Degree in Biomedical Engineering from Politecnico di Milano (Milan, Italy) and a Doctor of Philosophy in Engineering from the Australian National University (Canberra, Australia).

Researcher's projects

  • Closed-loop drug infusion for control of intraoperative arterial pressure
  • Real-time identification of patient-specific pharmacokinetics and pharmacodynamics in anaesthesia and intensive care settings (in collaboration with ACT Health)
  • Fluid-dynamic and mechanical modelling of cell damage and viability in direct cell injection applications (in collaboration with the ANU Lab for Advanced Biomaterials)
  • Big Data in Sleep Medicine (in collaboration with Canberra Sleep Clinic)
  • Our Health in Our Hands ANU Grand Challenge - Diabetes

Available student projects

  • Empirical modelling of the effects of microgravity on pulmonary ventilation and perfusion [systems physiology, in collaboration with the Space Medicine initiative of the ANU College of Health and Medicine]

  • Development of an explanatory model for the pathophysiology of of obstructive sleep apnea [biomechanics, systems and control, systems physiology]

Current student projects

  • A portable solution for field testing of the performance of polysmnography amplifiers (ongoing ENGN Capstone project) (in collaboration with Canberra Sleep Clinic)
  • In-silico comparison of knematics in total knee replacements for mechanically vs kinematically aligned implants (ongoing) (in collaboration with the Canberra Hospital Trauma and Orthopaedic Research Group)
  • A variable magnetic field generator device for bone cell proliferation experiments (ongoing ENGN Capstone project) (in collaboration with John Curtin School of Medical Research)
  • Virtualisation of a FPGA development board for e-learning application (ongoing)
  • Use of bayesian inference for patient-specific prediction of the time course of propofol anaesthesia (ongoing) (in collaboration with ACT health)

Past student projects

  • Technical validation of a novel methodology to conduct anterior rhinomanometry tests in CPAP therapy candidates (in collaboration with Canberra Sleep Clinic)


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Updated:  01 December 2023 / Responsible Officer:  Director (Research Services Division) / Page Contact:  Researchers