Professor Ted Maddess
PhD, FNAI
Professor - Fellow of the National Academy of Inventors
ANU College of Health and Medicine
Areas of expertise
- Sensory Systems 110906
- Ophthalmology 111301
- Neurocognitive Patterns And Neural Networks 170205
- Sensory Processes, Perception And Performance 170112
- Vision Science 111303
- Neurology And Neuromuscular Diseases 110904
- Other Psychology And Cognitive Sciences 1799
- Medical Devices 090304
Research interests
Visual field testing for eye diseases and development of such technologies
Commercialisation
Texture vision
Biography
Ted did his undergraduate degree at the University of British Columbia where he became fascinated with the diverse optical designs of eyes. In 1981 he came to the then Research School of Biological Sciences (now part of RSB) at the ANU to do a PhD on insect vision but finished up working on nonlinear adaptive mechanisms in mammalian visual cortex. Ted then briefly moved to the John Curtin School of Medical Research to carry on with the cortical work but instead exploited a retinal adaptation mechanism to invent a new stimulus for mapping the visual fields (perimetry) for diseases like glaucoma. The resulting patents are used in the FDT and Matrix perimeters sold by Carle Zeiss Meditech. That work caused Ted to work more on human vision in health and disease. In late 2012 his group moved to the new Clinical Suite of the ANU Eccles Institute for Neuroscience (EIN) at the John Curtin School of Medical Research. Ted is the recent past Director of a national research body: the ARC Vision Centre. His group is working with Konan Medical to deliver the world's first objective visual field test, the objectiveFIELD.
.
Publications
- Carle, C, James, A, Sabeti, F et al. 2022, 'Clustered Volleys Stimulus Presentation for Multifocal Objective Perimetry', Translational Vision Science & Technology, vol. 11, no. 2, pp. 1-10.
- Ali, E, Lueck, C, Carle, C et al. 2022, 'Response characteristics of objective perimetry in persons living with epilepsy', Journal of the Neurological Sciences, vol. 436, pp. 1-5.
- Thomson, K, Karouta, C, Sabeti, F et al. 2022, 'The safety and tolerability of levodopa eye drops for the treatment of ocular disorders: A randomized first-in-human study', Clinical and Translational Science, vol. 15, no. 11, pp. 2673-2684.
- Rai, B, Essex, R, Sabeti, F et al. 2021, 'An objective perimetry study of central versus peripheral sensitivities and delays in age-related macular degeneration', Translational Vision Science & Technology, vol. 10, no. 14, pp. 1-14.
- Rai, B, Maddess, T, Carle, C et al. 2021, 'Comparing Objective Perimetry, Matrix Perimetry, and Regional Retinal Thickness in Mild Diabetic Macular Edema', Translational Vision Science & Technology, vol. 10, no. 13, pp. 1-12.
- Sabeti, F, Lane, J, Rohan, M et al. 2021, 'Relationships between retinal structure and function and vision-related quality of life measures in advanced age-related macular degeneration', Graefe's Archive for Clinical and Experimental Ophthalmology, vol. 259, pp. 3687-3696.
- Ali, E, Carle, C, Lueck, C et al. 2021, 'Assessing migraine patients with multifocal pupillographic objective perimetry', BMC Neurology, vol. 21, no. 211, pp. 1-12.
- Sabeti, F, Lane, J, Rohan, M et al. 2021, 'Correlation of central versus peripheral macular structure-function with acuity in age-related macular degeneration', Translational Vision Science & Technology, vol. 10, no. 2, pp. 1-12.
- Maddess, T, Coy, D, Herrington, J et al. 2021, 'Learning complex texture discrimination', Journal of the Optical Society of America A, vol. 38, no. 3, pp. 449-455.
- Rai, B, Ashby, R, French, A et al. 2020, 'Rural-urban differences in myopia prevalence among myopes presenting to Bhutanese retinal clinical services: a 3-year national study', Graefe's Archive for Clinical and Experimental Ophthalmology, vol. 259, no. 3, pp. 613-621.
- Rai, B, Morley, M, Zangmo, P et al. 2020, 'Retinal laser services in Bhutan: A 3-year national survey', BMC Ophthalmology, vol. 20, no. 404, pp. 1-6.
- Abdullah, S, Sanderson, G, Husni, M et al. 2020, 'Insights for mfVEPs from perimetry using large spatial frequency-doubling and near frequency-doubling stimuli in glaucoma.', Documenta Ophthalmologica, vol. 141, pp. 44-55.
- Rai, B, Morley, M, Zangmo, P et al. 2020, 'Surgical management of vitreoretinal diseases in Bhutan: A 3-year national study', New Frontiers in Ophthalmology, vol. 6, pp. 1-5.
- Rai, B, Morley, M, Bernstein, P et al. 2020, 'Pattern of vitreo-retinal diseases at the national referral hospital in Bhutan: a retrospective, hospital-based study', BMC Ophthalmology, vol. 20, no. 51, pp. 1-11.
- Loutit, A, Shivdasani, M, Maddess, T et al. 2019, 'Peripheral nerve activation evokes machine-learnable signals in the dorsal column nuclei', Frontiers in Systems Neuroscience, vol. 13, pp. 11: 1-19.
- Barbosa, M, Maddess, T, Ahn, S et al. 2019, 'Novel morphometric analysis of higher order structure of human radial peri-papillary capillaries: relevance to retinal perfusion efficiency and age', Scientific Reports, vol. 9, no. 1.
- Pearce, J & Maddess, T 2019, 'The Clinical Interpretation of Changes in Intraocular Pressure Measurements Using Goldmann Applanation Tonometry: A Review', Journal of Glaucoma, vol. 28, no. 4, pp. 302-306.
- Carle, C, James, A, Rosli, Y et al. 2019, 'Localization of Neuronal Gain Control in the Pupillary Response', Frontiers in Neurology, vol. 10, no. 203, pp. 1-9pp.
- Lane, J, Robbins, R, Rohan, M et al. 2019, 'Caricaturing can improve facial expression recognition in low-resolution images and age-related macular degeneration', Journal of Vision, vol. 19, no. 6.
- Sabeti, F, Carle, C, Jaros, R et al. 2019, 'Objective Perimetry in Sporting-Related Mild Traumatic Brain Injury', Ophthalmology, vol. 126, no. 7, pp. 1053-1055.
- Maddess, T & Lueck, C 2019, 'Correlating structure with visual function in patients with multiple sclerosis: Where is this leading?', Clinical Neurophysiology, vol. 130, no. 1, pp. 157-159.
- Rai, B, Shresthra, M, Thapa, R et al. 2019, 'Pattern and Presentation of Vitreo-Retinal Diseases: An Analysis of Retrospective Data at a Tertiary Eye Care Center in Nepal', Asia-Pacific Academy of Ophthalmology, vol. 8, no. 6, pp. 481-488.
- Rai, B, Sabeti, F, Carle, C et al. 2019, 'Recovery dynamics of multifocal pupillographic objective perimetry from tropicamide dilation', Graefe's Archive for Clinical and Experimental Ophthalmology, vol. 258, pp. 191-200.
- Maddess, T, Jaros, R, Sabeti, F et al. 2018, 'Assessing concussion with multifocal pupillographic objective perimetry', Investigative Ophthalmology and Visual Science, vol. 59, no. 9.
- Lane, J, Rohan, M, Sabeti, F et al. 2018, 'Impacts of impaired face perception on social interactions and quality of life in age-related macular degeneration: A qualitative study and new community resources', PLOS ONE (Public Library of Science), vol. 13, no. 12, pp. 31pp.
- Lane, J, Rohan, M, Sabeti, F et al. 2018, 'Improving face identity perception in age-related macular degeneration via caricaturing', Scientific Reports, vol. 8, no. 15205, pp. 1-10.
- Carle, C, Rosli, Y, Ho, Y et al 2018, 'Retinotopic effects of visual attention revealed by dichoptic multifocal pupillography', Scientific Reports, vol. 8, no. 1, pp. 1-13.
- Sabeti, F, Sabeti, F, Carle, C et al 2018, 'Changes in Macular function with Multifocal Pupillography and its spatial correlation with severity of Diabetic Retinopathy', Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), ed. Donald C. Hood, ARVO, USA, pp. Meeting Abstract: 1893.
- Sabeti, F, Sabeti, F, Carle, C et al 2018, 'Changes in Macular function with Multifocal Pupillography and its spatial correlation with severity of Diabetic Retinopathy', Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), ed. Donald C. Hood, ARVO, USA, pp. Meeting Abstract: 1893.
- Sabeti, F, James, A, Carle, C et al. 2017, 'Comparing multifocal pupillographic objective perimetry (mfPOP) and multifocal visual evoked potentials (mfVEP) in retinal diseases', Scientific Reports, vol. 7, pp. 45847-45847.
- Maddess, T & Daria, V 2017, 'To BCVA, or not to BCVA, that is the question', Clinical and Experimental Ophthalmology, vol. 45, no. 5, pp. 437-439.
- Maddess, T & Lueck, C 2017, 'Multiple sclerosis seen through new eyes. Editorial on Afferent visual pathways in multiple sclerosis: a review', Clinical and Experimental Ophthalmology, vol. 45, no. 1, pp. 9-11.
- Loutit, A, Maddess, T, Redmond, S et al. 2017, 'Characterisation and functional mapping of surface potentials in the rat dorsal column nuclei', Journal of Physiology, vol. 595, no. 13, pp. 4507-4524.
- Pearce, J & Maddess, T 2017, 'Inter-visit test-retest variability of OCT in Glaucoma ', Optometry and Vision Science, vol. 94, no. 3, pp. 404-410.
- Numata, T, Maddess, T, Matsumoto, C et al. 2017, 'Exploring test-retest variability using high-resolution perimetry', Translational vision science & technology, vol. 6, no. 5, pp. 1-9pp.
- Pearce, J & Maddess, T 2016, 'Retest Variability in the Medmont M700 Automated Perimeter', Optometry and Vision Science, vol. 93, no. 3, pp. 272-280.
- Reilly, M, Villarreal, A, Maddess, T et al. 2015, 'Refined Frequency Doubling Perimetry Analysis Reaffirms Central Nervous System Control of Chronic Glaucomatous Neurodegeneration', Translational vision science & technology, vol. 4, no. 3, pp. 1-12.
- Carle, C, James, A, Kolic, M et al. 2015, 'Blue multifocal pupillographic objective perimetry in glaucoma', Investigative Ophthalmology and Visual Science, vol. 56, no. 11, pp. 6394-6403.
- Maddess, T 2015, 'Squiggly lines and wiggly data', Investigative Ophthalmology and Visual Science, vol. 56, no. 13, pp. 7806-7806.
- Potas, J, Gonvales de Castro, N, Maddess, T et al. 2015, 'Waveform Similarity Analysis: A Simple Template Comparing Approach for Detecting and Quantifying Noisy Evoked Compound Action Potentials', PLOS ONE (Public Library of Science), vol. 10, no. 9, pp. e0136992-e0136992.
- Sabeti, F, Nolan, C, James, AC et al 2015, 'Multifocal pupillography identifies changes in visual sensitivity according to severity of diabetic retinopathy in type 2 diabetes', Investigative Ophthalmology and Visual Science, vol. 56, no. 8, pp. 4504-4513.
- Seamons, J, Barbosa, MS, Bubna-Litic, A et al 2015, 'A lower bound on the number of mechanisms for discriminating fourth and higher order spatial correlations', Vision Research, vol. 108, pp. 41-48.
- Sponsel, W, Groth, S, Satsangi, N et al. 2014, 'Refined data analysis provides clinical evidence for central nervous system control of chronic glaucomatous neurodegeneration', Translational vision science & technology, vol. 3, no. 3, pp. 1-1.
- Maddess, T 2014, 'Modeling the relative influence of fixation and sampling errors on retest variability in perimetry', Graefe's Archive for Clinical and Experimental Ophthalmology, vol. 252, no. 10, pp. 1611-1619.
- Abdullah, S, Sanderson, G, James, AC et al 2014, 'Visual evoked potential and psychophysical contrast thresholds in glaucoma', Documenta Ophthalmologica, vol. 128, no. 2, pp. 111-120.
- Ali, EN, Maddess, T, James, AC, Voicu, C, Lueck, CJ, 2014, 'Pupillary response to sparse multifocal stimuli in multiple sclerosis patients', Multiple Sclerosis, 20:854-861.
- Barbosa, MS, Natoli, R, Valter, K et al 2014, 'Integral-geometry characterization of photobiomodulation effects on retinal vessel morphology', Biomedical Optics Express, vol. 5, no. 7, pp. 2317-2332.
- Carle, CF, James, AC, Kolic, M et al 2014, 'Luminance and colour variant pupil perimetry in glaucoma', Clinical & Experimental Ophthalmology, vol. 42, pp. 815-824.
- Sabeti, F, Maddess, T, Essex, RW., Saikal, A, James, AC & Carle, CF 2014, 'Multifocal pupillography in early age-related macular degeneration', Optometry and Vision Science, vol. 91, no. 8, pp. 904-915.
- Provis, J, Dubis, A, Maddess, T et al. 2013, 'Adaptation of the central retina for high acuity vision: Cones, the fovea and the avascular zone', Progress in Retinal and Eye Research, vol. 35, pp. 63-81.
- Barbosa, MS, Maddess, T & Bubna-Litic, A 2013, 'Locally countable properties and the perceptual salience of textures', Journal of the Optical Society of America A, vol. 30, no. 8, pp. 1687-1697.
- Carle, CF, James, AC & Maddess, T 2013, 'The pupillary response to color and luminance variant multifocal stimuli', Investigative Ophthalmology and Visual Science, vol. 54, no. 1, pp. 467-475.
- Sabeti, F, James, AC, Essex, RW et al 2013, 'Dichoptic multifocal visual evoked potentials identify local retinal dysfunction in age-related macular degeneration', Documenta Ophthalmologica, vol. 126, pp. 125-136.
- Sabeti, F, James, AC, Essex, RW et al 2013, 'Multifocal pupillography identifies retinal dysfunction in early age-related macular degeneration', Graefe's Archive for Clinical and Experimental Ophthalmology, vol. 251, no. 7, pp. 1707-1716.
- Maddess, T 2012, 'Pupil dynamics and response amplitude: only size matters', Investigative Ophthalmology and Visual Science, vol. 53, no. 12, pp. 7644-7644.
- Abdullah, S, Aldahlawi, N, Rosli, Y et al. 2012, 'Effect of Contrast, Stimulus Density, and Viewing Distance on Multifocal Steady-State Visual Evoked Potentials (MSVs)', Investigative Ophthalmology and Visual Science, vol. 53, no. 9, pp. 5527-5535.
- Abdullah, S, Vaegan, A, Boon, M et al. 2012, 'Contrast-response functions of the multifocal steady-state VEP (MSV)', Clinical Neurophysiology, vol. 123, no. 9, pp. 1865-1871.
- James, AC, Kolic, M, Bedford, SM etal 2012, 'Stimulus Parameters for Multifocal Pupillographic Objective Perimetry', Journal of Glaucoma, vol. 21, no. 9, pp. 571-578.
- Rosli, Y, Bedford, SM, James, AC, Maddess, T 2012, 'Photopic and scotopic multifocal pupillographic responses in age-related macular degeneration', Vision Research, vol. 69, pp. 42-48.
- Sabeti, F, Maddess, T, Essex, RW, James AC 2012, 'Multifocal pupillography identifies Ranibizumab-induced changes in retinal function for exudative age-related macular degeneration', Investigative Ophthalmology and Visual Science, vol. 53, no. 1, pp. 253-260.
- Maddess, T 2011, 'Frequency-Doubling Technology and Parasol Cells', Investigative Ophthalmology and Visual Science, vol. 52, no. 6, pp. 3759-3759.
- Maddess, T 2011, 'The influence of sampling errors on test-retest variability in perimetry', Investigative Ophthalmology and Visual Science, vol. 52, no. 2, pp. 1014-1022.
- Carle, C, James, AC, Kolic, M, Loh, YW, Maddess, T 2011, 'High resolution multifocal pupillographic objective perimetry in glaucoma', Investigative Ophthalmology and Visual Science, vol. 52, no. 1, pp. 604-610.
- Carle, C, Maddess, T & James, AC 2011, 'Contraction anisocoria: Segregation, summation, and saturation in the pupillary pathway', Investigative Ophthalmology and Visual Science, vol. 52, no. 5, pp. 2365-2371.
- Maddess, T., Ho, Y. L., Wong, S. S., Kolic, M., Goh, X. L., Carle, C. F. and James, A. C. (2011) 'Multifocal pupillographic perimetry with white and colored stimuli', Journal of Glaucoma, vol. 20, no. 6, pp. 336-343.
- Sabeti, F, James, AC & Maddess, T 2011, 'Spatial and temporal stimulus variants for multifocal pupillography of the central visual field', Vision Research, vol. 51, no. 2, pp. 303-310.
- Sabeti, F, Maddess, T, Essex, RW, James, AC 2011, 'Multifocal pupillographic assessment of age-related macular degeneration', Optometry and Vision Science, vol. 88 (Published ahead of Print), no. 12, pp. 9pp.
- Maddess, T, Hemmi, J & James, A 1998, 'Evidence for spatial aliasing effects in the Y-like cells of the magnocellular visual pathway', Vision Research, vol. 38, no. 12, pp. 1843-1859.
- Bell, A, James, AC, Kolic, M, Essex, RW, Maddess, T 2009, 'Dichoptic multifocal pupillography reveals afferent visual field defects in early type 2 diabetes', Investigative Ophthalmology and Visual Science, vol. 51, pp. 602-608.
- Nagai, Y, Taylor, R, Lo, Y et al. 2009, 'Discrimination of complex form by simple oscillator networks', Network: Computation in Neural Systems, vol. 20, no. 4, pp. 233-252.
- Rosli, Y, Bedford, S & Maddess, T 2009, 'Low spatial frequency channels and the spatial frequency doubling illusion', Investigative Ophthalmology and Visual Science, vol. 50, no. 4, pp. 1956-1963.
- Bell, A & Maddess, T 2009, 'Tilt of the outer hair cell lattice: origin of dual tuning tips and cochlear bandwidth', in N Cooper, D Kemp (ed.), Concepts and Challenges in the Biophysics of Hearing: Proceedings of the 10th International Workshop on the Mechanics of Hearing, World Scientific Publishing Company, UK, pp. 310-318.
- Maddess, T, Bedford, SM, Goh, XL, James, AC 2009, 'Multifocal pupillographic visual field testing in glaucoma', Clinical and Experimental Ophthalmology, vol. 37, pp. 678-686.
- Rosli, Y, Maddess, T, Dawel, A, James, AC 2009, 'Multifocal frequency-doubling pattern visual evoked responses to dichoptic stimulation', Clinical Neurophysiology, vol. 120, no. 12, pp. 2100-2108.
- Taylor, R, Maddess, T & Nagai, Y 2008, 'Spatial biases and computational constraints on the encoding of complex local image structure', Journal of Vision, vol. 8(7), no. 19, pp. 1-13.
- Nagai, Y & Maddess, T 2008, 'Discrimination of binary isotrigon textures by 1-D oscillator network of cascade arrangement', Memoirs of the Kokushikan University Centre for Information Science, vol. 29, pp. 1-12.
- Maddess, T, Nagai, Y, Victor, J et al. 2007, 'Multilevel isotrigon textures', Journal of the Optical Society of America A, vol. 24, no. 2, pp. 278-293.
- Maddess, T, James, AC, Ruseckaite, R, Bowman, EA 2006, 'Hierarchical decomposition of dichoptic multifocal visual evoked potentials', Visual Neuroscience, vol. 23, pp. 703-712.
- Ruseckaite, R, Maddess, T, Danta, G, James, AC 2006, 'Frequency doubling illlusion VEPs and automated perimetry in multiple sclerosis', Documenta Ophthalmologica, vol. 113, pp. 29-41.
- James, AC, Ruseckaite, R & Maddess, T 2005, 'Effect of temporal sparseness and dichoptic presentation on multifocal visual evoked potentials', Visual Neuroscience, vol. 22, pp. 45-54.
- Maddess, T, James, AC & Bowman, EA 2005, 'Contrast response of temporally sparse dichoptic multifocal visual evoked potentials', Visual Neuroscience, vol. 225, pp. 153-162.
- Ruseckaite, R, Maddess, T, Danta, G, Lueck, CJ, James, AC 2005, 'Sparse multifocal stimuli for the detection of Multiple Sclerosis', Annals of Neurology, vol. 57, no. 6, pp. 905-913.
- Maddess, T, Nagai, Y, James, AC, Ankiewcz, A 2004, 'Binary and Ternary Textures Containing Higher-Order Spatial Correlations', Vision Research, vol. 44, pp. 1093-1113.
- Maddess, T, Rascher, U, Siebke, K et al. 2002, 'Definition and evaluation of the spatiotemporal variations in chlorophyll fluorescence during the phases of CAM and during endogenous rhythms in continuous light, in thick leaves of Kalanchoe daigremontiana', Plant Biology, vol. 4, pp. 446-455.
- Maddess, T & Nagai, Y 2001, 'Discriminating isotrigon textures', Vision Research, vol. 41, pp. 3837-3860.
- Maddess, T, Severt, W & Stange, F 2001, 'Comparison of three tests using the frequency doubling illusion to diagnose glaucoma', Clinical and Experimental Ophthalmology, vol. 29, pp. 359-367.
- Hemmi, J, Maddess, T & Mark, R 2000, 'Spectral sensitivity of photoreceptors in an Australian marsupial, the tammar wallaby (Macropus eugenii)', Vision Research, vol. 40, pp. 591-599.
- Maddess, T, James, AC, Goldberg, I, Wine, S, Dobinson, J 2000, 'A spatial frequency-doubling illusion-based pattern electroretinogram for glaucoma.', Investigative Ophthalmology and Visual Science, vol. 41, pp. 3818-3826.
- Maddess, T, James, AC, Goldberg, I, Wine, S, Dobinson, J 2000, 'Comparing a parallel PERG, automated perimetry and frequency doubling thresholds.', Investigative Ophthalmology and Visual Science, vol. 41, pp. 3827-3823.
- Maddess, T & Kulikowski, J 1999, 'Apparent fineness of stationary compound gratings', Vision Research, vol. 39, pp. 3404-3416.
- Maddess, T, Goldberg, I, Dobinson, J, Wine, S, Welsh, AH, James, AC 1999, 'Testing for Glaucoma with the spatial frequency doubling illusion', Vision Research, vol. 39, pp. 4258-4273.
Projects and Grants
Grants information is drawn from ARIES. To add or update Projects or Grants information please contact your College Research Office.
- Rapid and objective eye and brain testing for better management of ophthalmic and neurological diseases (Primary Investigator)
- Identifying functional biomarkers in eyes at risk of vision loss in Type 2 Diabetes (Primary Investigator)
- Objective Perimetry Methods (Primary Investigator)
- Validating novel means of quantifying blood vessel networks and similar micro-structures for quantitative 3D imaging (Primary Investigator)
- Macular Pigment in Age-related Macular Degeneration structure versus function (Secondary Investigator)
- Novel functional testing for macular degeneration (Primary Investigator)
- Novel functional testing for early diabetic retinopathy (Primary Investigator)
- ARC Centre of Excellence - Vision Science (Primary Investigator)
