Associate Professor Rachel W. Li

MD, PhD.
Associate Professor, Group Leader, Trauma and Orthopaedic Research Laboratory
ANU College of Health and Medicine

Areas of expertise

  • Orthopaedics 110314
  • Biomaterials 090301
  • Rheumatology And Arthritis 110322
  • Pharmacology And Pharmaceutical Sciences 1115
  • Immunology Not Elsewhere Classified 110799

Biography

 

Short Bio:  Associate Professor Rachel W. Li was a clinician, liver diseases specialist. She created an Endoscopic Drug Delivery device which was used in the stomach and liver cancer patients with acute haemorrhage. She received a National Innovation Award from Chinese Medical Association. She completed PhD in Southern Cross University and postdoctoral fellowship in USA, then an Assistant Professor of Clinical Pathology, University of Hawaii. She started her laboratory research focusing on the interplay among orthopaedic implant, bone and immune system after returning to Australia. She pinioned orthopaedic laboratory research in ACT region, which has not only produced high level science and emerging scientists, but all resulted in her being awarded funding from ARC, NHMRC, and CORE.

 

Researcher's projects

Osteo-immunology: Interplay of osteoblasts and inflammatory cells in primary and revision total joint arthroplasty  

Clinical trial: athrofibrosis - interplay of ECM fibroblasts with inflammatory cells post total knee arthroplasty

Personalised medicine: Exosome miRNAs as regulators of mRNAs in osteolysis of the patients undergoing revision total joint replacement.

Bio material development: Biomimetic gels for co-growth of osteoblasts and osteoclasts

Bio material development: Magnesium alloys for biodegradable, resorbable and antibacterial implants. This project requires in vitro and in vivo experiment.  

 

 

 

Available student projects

  1. Biomaterials, metal and polyethylene, for orthopaedic implants in vitro testing
  2. Biomaterials for orthopaedic implants preclinical trial (surgery) in vivo on medium/large animals
  3. Patient recruitment, sampling and mRNA and miRNA sequencing (for clinical PhD researchers)
  4. Natural compounds in vitro testing for anti-inflammatory and antibacterial activity

Current student projects

The osseointegration and antimicrobial properties of AgSrPO4Mg

Circulating miRNA and osteolysis around hip and knee arthroplasty

Bioresorbable metals for osteosynthesis in maxillofacial surgery

Athrofibrosis - interplay of ECM fibroblasts with inflammatory cells post total knee arthroplasty

 

 

Publications

Projects and Grants

Grants information is drawn from ARIES. To add or update Projects or Grants information please contact your College Research Office.

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Updated:  23 April 2024 / Responsible Officer:  Director (Research Services Division) / Page Contact:  Researchers