Dr James Hennessy
Areas of expertise
- Biocatalysis And Enzyme Technology 100301
- Biochemistry And Cell Biology 0601
- Synthetic Biology 060113
- Agricultural Biotechnology 1001
- Industrial Biotechnology 1003
- Bioremediation 100203
- Analytical Biochemistry 060101
- Organic Chemistry 0305
- Medicinal And Biomolecular Chemistry 0304
- Genetics 0604
- Cell Metabolism 060104
- Structural Biology (Incl. Macromolecular Modelling) 060112
Biography
Appointments
10/2009 - Present, Postdoctoral Fellow, Research School of Chemistry, Australian National University, Canberra.
Education
2006 - 2009, Ph.D. Chemistry (Biocatalysis), Joint position at CSIRO Ecosystem Sciences and the Research School of Chemistry, Australian National University, Canberra.
Thesis title - Modifying Enzyme Catalytic Pathways.
2000 - 2005, M.Chem. Chemistry (First Class Honours), Department of Chemistry, University of Aberdeen, Scotland.
Thesis title – The Use of Nitrate Esters in the Synthesis of α-Amino Acid Derivatives via α-and β-Alanyl Radical Intermediates.
Publications
- Alissandratos, A, Kim, H, Matthews, H et al. 2013, 'Clostridium carboxidivorans strain P7T recombinant formate dehydrogenase catalyzes reduction of CO2 to formate', Applied and Environmental Microbiology, vol. 79, no. 2, pp. 741-744.
- Walker, I, Hennessy, J, Ollis, D et al. 2012, 'Substrate-induced conformational change and isomerase activity of dienelactone hydrolase and its site-specific mutants', ChemBioChem, vol. 13, no. 11, pp. 1645-1651.
- Lapalikar, G, Taylor, M, Warden, A et al. 2012, 'Cofactor promiscuity among F420-dependent reductases enables them to catalyse both oxidation and reduction of the same substrate', Catalysis Science and Technology, vol. 2, no. 8, pp. 1560-1567.
- Stigers, D, Watts, Z, Hennessy, J et al. 2011, 'Incorporation of chlorinated analogues of aliphatic amino acids during cell-free protein synthesis', Chemical Communications, vol. 47, no. 6, pp. 1839-1841.
