Dr Stephen Fairweather

Doctor of Philosophy (Biochemistry)
Post-Doctoral Research Fellow
College of Science
T: +612 6197 0048

Areas of expertise

  • Receptors And Membrane Biology 060110

Research interests

Membrane Physiology and Transporters

Protein-Protein Interactions

Electrophysiology

Amino Acid Metabolism

Membrane Transporter Phamacology

Protein Molecular Dynamic Simulations

Biography

My research focuses on the biochemistry and physiology of membrane transporter proteins. Membrane transporters exist in all biological membranes and mediate the flux of nutrients, ions, and xenobiotics both in and out of living cells. We use molecular biology, biochemical and analytical chemistry methods for the investigation of structure-activity relationships in these proteins. Current research interests include elucidating the identity, function and importance of amino acid transporters in the major human pathogens from the phylum Apicomplexa: Toxoplasma gondii and Plasmodium spp. I am currently employed as a post-doctoral scientist in the Laboratory of Assoc. Prof. Giel van Dooren in the Research School of Biology and am enjoying working with the molecular parasitologists, combining the study of isolated transporters proteins with the genetics and cell biology methods that my brilliant colleagues use to study these organisms. I am immensely interested in showing how the chemistry of membrane transporters are vital for understanding their more obviously manifest biological and physiological roles in the whole organisms. I enjoy very much applying new techniques into the novel setting of membrane physiology. Recently this includes widening our research expertise to incorporate high resolution metabolomic techniques such as GC-QQQ and LC-MS/MS, and the expression of apicomplexan membrane proteins in yeast and X.laevis oocytes for high-resolution functional and structural analysis of these proteins.

Publications

Projects and Grants

Grants information is drawn from ARIES. To add or update Projects or Grants information please contact your College Research Office.

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Updated:  26 September 2021 / Responsible Officer:  Director (Research Services Division) / Page Contact:  Researchers