Areas of expertise

• Organic Chemical Synthesis 030503
• Physical Organic Chemistry 030505
• Polymerisation Mechanisms 030305
• Characterisation Of Biological Macromolecules 030403
• Nanochemistry And Supramolecular Chemistry 030302
• Industrial Chemistry 039903
• Free Radical Chemistry 030501
• Proteins And Peptides 030406
• Separation Science 030108
• Environmental Biotechnology 1002
• Medicinal And Biomolecular Chemistry 0304
• Organic Chemistry 0305
• Theoretical And Computational Chemistry 0307
• Nanotechnology 1007

Publications

• Randone, L, Onagi, H, Lincoln, S et al. 2019, 'Direct Synthesis of an Oligomeric Series of Interlocked, Cyclodextrin-Based [c2]Daisy Chains', European Journal of Organic Chemistry, vol. 2019, no. 21, pp. 3495-3502.
• Alissandratos, A, Hartley, C, French, N et al 2019, 'One-Pot Multienzymatic Transformation of NH3 , CO2 , and Ornithine into the Organic Nitrogen Plant Fertilizer Citrulline Using a Single Recombinant Lysate of E. coli', ACS Sustainable Chemistry & Engineering, vol. 7, no. 9, pp. 8522-8529.
• Loan, T, Easton, C & Alissandratos, A 2019, 'Recombinant cell-lysate-catalysed synthesis of uridine-5'-triphosphate from nucleobase and ribose, and without addition of ATP', New Biotechnology, vol. 49, pp. 104-111.
• Chan, B, Easton, C & Radom, L 2018, 'Effect of Hydrogen Bonding and Partial Deprotonation on the Oxidation of Peptides', Journal of Physical Chemistry A, vol. 122, no. 6, pp. 1741-1746pp.
• Hennessy, J, Latter, M, Philbrook, A et al. 2018, 'Hyperthermophilic Carbamate Kinase Stability and Anabolic In Vitro Activity at Alkaline pH', Applied and Environmental Microbiology, vol. 84, no. 3, pp. 1-13.
• Robinson, K, Easton, C, Dulhunty, A et al. 2018, 'Exploiting Peptidomimetics to Synthesize Compounds That Activate Ryanodine Receptor Calcium Release Channels', ChemMedChem, vol. 13, no. 18, pp. 1957-1971pp.
• Hong, N, Petrovic, D, Lee, Z et al. 2018, 'The evolution of multiple active site configurations in a designed enzyme', Nature Communications, vol. 9, pp. 1-10.
• Esquirol, L, Peat, T, Wilding, M et al. 2018, 'An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme', Journal of Biological Chemistry, vol. 293, no. 20, pp. 7880-7891pp.
• Rouse, C, Martin, A, Easton, C et al. 2017, 'A Peptide Amphiphile Organogelator of Polar Organic Solvents', Scientific Reports, vol. 7, pp. 43668-43668.
• McTernan, H, Ngo, H, Pham, D et al. 2017, 'Host-Guest Chemistry of Linked β- and γ-Cyclodextrin Dimers and 1- and 2-Naphthyl-Sulfonamide Substituted Poly(acrylate)s in Aqueous Solution', ChemistrySelect, vol. 2, no. 4, pp. 1421-1430pp..
• Chan, B, Moran, D, Easton, C et al. 2017, 'Impact of Hydrogen Bonding on the Susceptibility of Peptides to Oxidation', Chemistry - An Asian Journal, vol. 12, no. 13, pp. 1485-1489.
• Cao, F, Gamble, A, Onagi, H et al. 2017, 'Detection of Biosynthetic Precursors, Discovery of Glycosylated Forms, and Homeostasis of Calcitonin in Human Cancer Cells', Analytical Chemistry, vol. 89, no. 13, pp. 6992-6999.
• Chan, B, Moran, D, Easton, C et al. 2017, 'Impact of Hydrogen Bonding on the Susceptibility of Peptides to Oxidation', Chemistry - An Asian Journal, vol. 12, no. 13, pp. 1485-1489.
• Easton, C, Yan, L, Pham, D et al. 2017, 'ß-Cyclodextrin- and adamantyl-substituted poly(acrylate) self-assembling aqueous networks designed for controlled complexation and release of small molecules', Beilstein Journal of Organic Chemistry, vol. 13, pp. 1879-1892.
• Chan, B, Karton, A, Easton, C et al. 2016, 'α-Hydrogen Abstraction by .OH and .SH Radicals from Amino Acids and Their Peptide Derivatives', Journal of Chemical Theory and Computation (JCTC), vol. 12, no. 4, pp. 1606-1613.
• Liutkus, M, Fraser, S, Caron, K et al. 2016, 'Peptide Synthesis through Cell-Free Expression of Fusion Proteins Incorporating Modified Amino Acids as Latent Cleavage Sites for Peptide Release', ChemBioChem, vol. 17, no. 10, pp. 908-912pp.
• Alissandratos, A, Caron, K, Loan, T et al 2016, 'ATP Recycling with Cell Lysate for Enzyme-Catalyzed Chemical Synthesis, Protein Expression and PCR', ACS Chemical Biology, vol. 11, no. 12, pp. 3289-3293.
• Wong, A, Little, M, Caldicott, D et al. 2015, 'Analytically confirmed recreational use of Phenibut (β-phenyl-γ-aminobutyric acid) bought over the internet', Clinical Toxicology (Taylor & Francis), vol. 53, no. 7, pp. 783-784.
• Amos, R, Easton, C, Heinroth, F et al. 2015, 'Hydrogen from Formic Acid via Its Selective Disproportionation over Nanodomain-Modified Zeolites', ACS Catalysis, vol. 5, no. 7, pp. 4353-4362.
• Amos, R, Heinroth, F, Chan, B et al. 2015, 'Hydrogen from Formic Acid via Its Selective Disproportionation over Nanodomain-Modified Zeolites', ACS Catalysis, vol. 5, no. 7, pp. 4353-4362.
• Wong, A, Little, M, Caldicott, D et al. 2015, 'Analytically confirmed recreational use of Phenibut (β-phenyl-γ-aminobutyric acid) bought over the internet', Clinical Toxicology (Taylor & Francis), vol. 53, no. 7, pp. 783-784.
• Loh, K, Smith, N, Onagi, H et al. 2015, 'A Cyclodextrin-Based Photoresponsive Molecular Gate that Functions Independently of Either Solvent or Potentially Competitive Guests', Chemistry - An Asian Journal, vol. 10, no. 11, pp. 2328-2332.
• Alissandratos, A & Easton, C 2015, 'Biocatalysis for the application of CO2 as a chemical feedstock', Beilstein Journal of Organic Chemistry, vol. 11, pp. 2370-2387.
• Balotra, S, Newman, J, Cowieson, N et al. 2015, 'X-ray structure of the amidase domain of AtzF, the allophanate hydrolase from the cyanuric acid-mineralizing multienzyme complex', Applied and Environmental Microbiology, vol. 81, no. 2, pp. 470-480.
• Fraser, S & Easton, C 2015, 'Biosynthetic incorporation of fluorinated amino acids into peptides and proteins', Australian Journal of Chemistry, vol. 68, no. 1, pp. 9-12.
• Amos, R, Chan, B, Easton, C et al. 2015, 'Hydrogen-atom abstraction from a model amino acid: dependence on the attacking radical', Journal of Physical Chemistry B, vol. 119, no. 3, pp. 783-788.
• Pham, D, Nguyen, H, Lincoln, S et al. 2015, 'Complexation of dodecyl-substituted poly(acrylate) by linked β-cyclodextrin dimers and trimers in aqueous solution', Polymer Science - Series A, vol. 53, no. 10, pp. 1278-1286.
• Chan, B, Easton, C & Radom, L 2015, 'Outcome-changing effect of polarity reversal in hydrogen-atom-abstraction reactions', Journal of Physical Chemistry A, vol. 119, no. 16, pp. 3843-3847.
• Alissandratos, A, Kim, H & Easton, C 2014, 'Formate production through carbon dioxide hydrogenation with recombinant whole cell biocatalysts', Bioresource Technology, vol. 164, pp. 7-11.
• Amos, R, Heinroth, F, Chan, B et al. 2014, 'Hydrogen from Formic Acid through Its Selective Disproportionation over Sodium Germanate-A Non-Transition-Metal Catalysis System', Angewandte Chemie International Edition, vol. 53, no. 42, pp. 11275-11279.
• Alissandratos, A, Kim, H, Matthews, H et al. 2013, 'Clostridium carboxidivorans strain P7T recombinant formate dehydrogenase catalyzes reduction of CO2 to formate', Applied and Environmental Microbiology, vol. 79, no. 2, pp. 741-744.
• Nguyen, H, Pham, D, Lincoln, S et al. 2013, 'Host-guest chemistry of linked β-cyclodextrin trimers and adamantyl substituted poly(acrylate)s in aqueous solution', Polymer Chemistry, vol. 4, no. 3, pp. 820-829.
• Philbrook, A, Earnshaw, S, Easton, C et al. 2013, 'Co-polymerization analysis of thermosetting resins using ¹H-¹⁵N-¹³C triple resonance NMR spectroscopy', Journal of Applied Polymer Science, vol. 128, no. 5, pp. 3375-3381.
• Cao, F & Easton, C 2013, 'Production and regulation of levels of amidated peptide hormones', Australian Journal of Chemistry, vol. 66, no. 3, pp. 297-307.
• Easton, C, ed., 2013, Beckwith memorial symposium on free radical chemistry.
• Philbrook, A, Alissandratos, A & Easton, C 2013, 'Biochemical processes for generating fuels and commodity chemicals from lignocellulosic biomass', in M. Petre (ed.), Environmental Biotechnology - New Approaches and Prospective Applications, InTech Open Access Publisher, Rijeka, Croatia, pp. 39-64.
• Zhu, Y, Wu, N & Easton, C 2013, 'MICRO SEGMENTED FLOW FUNCTIONAL ELEMENTS AND BIOTECHNICAL APPLICATIONS', Frontiers in Bioscience, vol. 5, no. 1, pp. 284-304.
• Arthur, I, Hennessy, J, Padmakshan, D et al. 2013, 'In situ deprotection and incorporation of unnatural amino acids during cell-free protein synthesis', Chemistry, A European Journal, vol. 19, no. 21, pp. 6824-6830.
• Alissandratos, A, Kim, H & Easton, C 2013, 'Formate production through biocatalysis', Bioengineered, vol. 4, no. 5, pp. 348-350.
• Nguyen, H, Pham, D, Easton, C et al. 2013, 'Complexation of crystal violet, pyronine B, and rhodamine B by linked β-cyclodextrin trimers', Australian Journal of Chemistry, vol. 66, no. 9, pp. 1057-1064.
• Harada, T, Giorgio, L, Harris, T et al. 2013, 'Diamide linked γ-cyclodextrin dimers as molecular-scale delivery systems for the medicinal pigment curcumin to prostate cancer cells', Molecular Pharmaceutics, vol. 10, no. 12, pp. 4481-4490.
• Philbrook, A, Earnshaw, S & Easton, C 2012, 'Cross-links between soy protein residues and urea formaldehyde resins', Polymer preprints, vol. 243, no. 1, pp. 667-668.
• Muirhead, K, Earnshaw, S, Easton, C et al. 2012, 'Incorporation of guanidine and ethylguanidine into thermosetting resins', Journal of Applied Polymer Science, vol. 125, no. S2, pp. E372-E377.
• Lapalikar, G, Taylor, M, Warden, A et al. 2012, 'Cofactor promiscuity among F₄₂₀-dependent reductases enables them to catalyse both oxidation and reduction of the same substrate', Catalysis Science and Technology, vol. 2, no. 8, pp. 1560-1567.
• Walker, I, Hennessy, J, Ollis, D et al. 2012, 'Substrate-induced conformational change and isomerase activity of dienelactone hydrolase and its site-specific mutants', ChemBioChem, vol. 13, no. 11, pp. 1645-1651.
• Chan, B, O'Reilly, R, Easton, C et al. 2012, 'Reactivities of amino acid derivatives toward hydrogen abstraction by Cl• and OH•', Journal of Organic Chemistry, vol. 77, no. 21, pp. 9807-9812.
• Morris, K, Cao, F, Onagi, H et al. 2012, 'Prohormone-substrate peptide sequence recognition by peptidylglycine α-amidating monooxygenase and its reflection in increased glycolate inhibitor potency', Bioorganic and Medicinal Chemistry Letters, vol. 22, no. 23, pp. 7015-7018.
• Hennessy, J, Philbrook, A, Bartkus, D et al. 2012, Methods of producing carbamoyl phosphate and urea.
• Stigers, D, Watts, Z, Hennessy, J et al. 2011, 'Incorporation of chlorinated analogues of aliphatic amino acids during cell-free protein synthesis', Chemical Communications, vol. 47, no. 6, pp. 1839-1841.
• Harada, T, Pham, D, Leung, M et al. 2011, 'Cooperative binding and stabilization of the medicinal pigment curcumin by diamide linked γ-cyclodextrin dimers: a spectroscopic characterization', Journal of Physical Chemistry B, vol. 115, no. 5, pp. 1268-1274.
• Ho, J, Coote, M & Easton, C 2011, 'The distal effect of N-electron-withdrawing groups on the stability of peptide carbon radicals', Australian Journal of Chemistry, vol. 64, no. 4, pp. 403-408.
• Barlow, C, Wright, A, Easton, C et al. 2011, 'Gas-phase ion-molecule reactions using regioselectively generated radical cations to model oxidative damage and probe radical sites in peptides', Organic and Biomolecular Chemistry, vol. 9, no. 10, pp. 3733-3745.
• Wu, N, Courtois, F, Surjadi, R et al. 2011, 'Enzyme synthesis and activity assay in microfluidic droplets on a chip', Engineering in Life Sciences, vol. 11, no. 2, pp. 157-164.
• Wu, N, Oakeshott, J, Easton, C et al. 2011, 'A double-emulsion microfluidic platform for in vitro green fluorescent protein expression', Journal of Micromechanics and Microengineering, vol. 21, no. 5, pp. 054032/1-7.
• Wang, J, Li, L, Guo, X et al. 2011, 'Aggregation of hydrophobic substituents of poly(acrylate)s and their competitive complexation by β- and γ-cyclodextrins and their linked dimers in aqueous solution', Industrial and Engineering Chemistry Research, vol. 50, no. 12, pp. 7566-7571.
• Ho, J, Coote, M & Easton, C 2011, 'Validation of the distal effect of electron-withdrawing groups on the stability of peptide enolates and its exploitation in the controlled stereochemical inversion of amino acid derivatives', Journal of Organic Chemistry, vol. 76, no. 15, pp. 5907-5914.
• Clinton, B, Warden, A, Haboury, S et al. 2011, 'Bacterial degradation of strobilurin fungicides: a role for a promiscuous methyl esterase activity of the subtilisin proteases?', Biocatalysis and Biotransformation, vol. 29, no. 4, pp. 119-129.
• Cao, F, Gamble, A, Kim, H et al. 2011, 'Potent and selective inhibitors of human peptidylglycine α-amidating monooxygenase', RSC Medicinal Chemistry (Formerly MedChemComm), vol. 2, no. 8, pp. 760-763.
• O'Rielly, R, Chan, B, Taylor, M et al. 2011, 'Hydrogen abstraction by chlorine atom from amino acids: remarkable influence of polar effects on regioselectivity', Journal of the American Chemical Society, vol. 133, no. 41, pp. 16553-16559.
• Wang, J, Pham, D, Kee, T et al. 2011, 'Aggregation and host-guest interactions in dansyl-substituted poly(acrylate)s in the presence of β-cyclodextrin and a β-cyclodextrin dimer in aqueous solution: a UV-vis, fluorescence, 1H NMR, and rheological study', Macromolecules, vol. 44, no. 24, pp. 9782-9791.
• Easton, C & Onagi, H 2010, 'Cyclodextrins as molecular reactors', in Udo Brinker and Jean-Luc Mieusset (ed.), Molecular Encapsulation: Organic Reactions in Constrained Systems, John Wiley & Sons Inc, Chichester, United Kingdom, pp. 71-90.
• Wu, N, Oakeshott, J, Brown, S et al. 2010, 'Microfluidic droplet technique for in vitro directed evolution', Australian Journal of Chemistry, vol. 63, no. 9, pp. 1313-1325.
• Ngo, H, Clements, P, Easton, C et al. 2010, 'Supramolecular Chemistry of Pyronines B and Y, β-Cyclodextrin and Linked β-Cyclodextrin Dimers.', Australian Journal of Chemistry, vol. 63, no. 4, pp. 687-692.
• Pham, D, Ngo, H, Lincoln, S et al. 2010, 'Synthesis of C6^A-to-C6^A and C3^A-to-C3^A diamide linked γ-cyclodextrin dimers', Tetrahedron, vol. 66, no. 15, pp. 2895-2898.
• Ho, J, Easton, C & Coote, M 2010, 'The Distal Effect of Electron-Withdrawing Groups and Hydrogen Bonding on the Stability of Peptide Enolates', Journal of the American Chemical Society, vol. 132, no. 15, pp. 5515-5521.
• Guo, X, Wang, J, Li, L et al. 2010, 'Tunable Polymeric Hydrogels Assembled by Competitive Complexation between Cyclodextrin Dimers and Adamantyl Substituted Poly(acrylate)s', AIChE Journal, vol. 56, no. 11, pp. 3021-3024.
• Wu, N, Courtois, F, Zhu, Y et al. 2010, 'Management of the diffusion of 4-methylumbelliferone across phases in microdroplet-based systems for in vitro protein evolution', Electrophoresis, vol. 31, no. 18, pp. 3121-3128.
• Wu, N, Zhu, Y, Brown, S et al. 2009, 'A PMMA microfluidic droplet platform for in vitro protein expression using crude E. coli S30 extract', Lab on a Chip, vol. 9, no. 23, pp. 3391-3398.
• Easton, C, Onagi, H, Dawson, R et al. 2009, 'Cyclodextrin nanoscale devices', Chemistry in Australia, vol. 76, no. 1, Feb, pp. 8-12 & 22.
• Jackson, C, Weir, K, Herlt, A et al. 2009, 'Structure-based rational design of a phosphotriesterase', Applied and Environmental Microbiology, vol. 75, no. 15, pp. 5153-5156.
• Watts, Z & Easton, C 2009, 'Peculiar stability of amino acids and peptides from a radical perspective', Journal of the American Chemical Society, vol. 131, no. 32, pp. 11323-11325.
• Khurana, J, Jackson, C, Scott, C et al. 2009, 'Characterization of the phenylurea hydrolases A and B: founding members of a novel amidohydrolase subgroup', Biochemical Journal, vol. 418, no. 2, pp. 431-441.
• Taylor, M, Ivanic, S, Wood, G et al. 2009, 'Hydrogen abstraction by chlorine atom from small organic molecules containing amino acid functionalities: an assessment of theoretical procedures', Journal of Physical Chemistry A, vol. 113, no. 43, pp. 11817-11832.
• Pham, D, Clements, P, Easton, C et al. 2009, 'Dimerisation and complexation of 6-(4'-t-butylphenylamino)naphthalene-2-sulphonate by β-cyclodextrin and linked β-cyclodextrin dimers', Supramolecular Chemistry, vol. 21, no. 6, p. 17.
• Pham, D, Clements, P, Easton, C et al. 2008, 'Complexation of 6-(4'-(toluidinyl)naphthalene-2-sulfonate by β-cyclodextrin and linked β-cyclodextrin dimers', New Journal of Chemistry, vol. 32, no. 4, pp. 712-718.
• Dawson, R, Maniam, S, Lincoln, S et al. 2008, 'Synthesis of α-cyclodextrin [2]-rotaxanes using chlorotriazine capping reagents', Organic and Biomolecular Chemistry, vol. 6, no. 10, pp. 1814-1821.
• Maniam, S, Cieslinski, M, Lincoln, S et al. 2008, 'Molecular fibers and wires in solid-state and solution self-assemblies of cyclodextrin [2]rotaxanes', Organic Letters, vol. 10, no. 10, pp. 1885-1888.
• Dawson, R, Lincoln, S & Easton, C 2008, 'The foundation of a light driven molecular muscle based on stilbene and α-cyclodextrin', Chemical Communications, no. 34, pp. 3980-3982.
• Wu, N, Zhu, Y, Leech, P et al. 2008, 'Microdroplets based detection using laser induced fluorescence for evolving new enzyme in a microfluidic device', European Conference on Microfluidics 2008, ed. Colin S, Morini GL, Societe Hydrotechnique de France, Bologne, Italy, pp. 1-8.
• Pham, D, Clements, P, Easton, C et al. 2008, '¹H NMR studies of enantioselective host-guest complexation by modified β-cyclodextrins and their europium(III) complexes', Tetrahedron: Asymmetry, vol. 19, no. 2, pp. 167-175.
• Philbrook, A, Easton, C, Earnshaw, S et al. 2007, 'Fluorescent tags for amino resins', Polymer preprints, vol. 48, no. 2, pp. 496-497.
• Wu, N, Zhu, Y, Leech, P et al. 2007, 'Effects of surfactants on the formation of microdroplets in the flow focusing microfluidic device', BioMEMS and Nanotechnology III, ed. D V Nicolau, D Abbott, K Kalantar-Zadeh, T Di Matteo, S M Bezrukov, SPIE, USA, pp. 67990C/1-8.
• Padmakshan, D, Bennett, S, Otting, G et al. 2007, 'Stereocontrolled synthesis of (S)-Y-fluoroleucine', Synlett, vol. 2007, no. 7, pp. 1083-1084.
• Dawson, R, Easton, C, Lincoln, S et al. 2007, 'Stilbene and α-cyclodextrin as the basis of a light driven molecular muscle', Asian Cyclodextrin Conference (ACC 2007), ed. Koji Kano, Doshisha University, Kyoto, Japan, pp. 84-91.
• Maniam, S, Lincoln, S & Easton, C 2007, 'Developing chemistry for the synthesis of three-stationed rotaxane molecular switches', Asian Cyclodextrin Conference (ACC 2007), ed. Koji Kano, Doshisha University, Kyoto, Japan, pp. 110-117.
• Lincoln, S & Easton, C 2007, 'Aspects of cyclodextrin polymers', Asian Cyclodextrin Conference (ACC 2007), ed. Koji Kano, Doshisha University, Kyoto, Japan, pp. 31-41.
• Hamilton, E, Berg, H, Easton, C et al. 2006, 'The effect of taurine depletion on the contractile properties and fatigue in fast-twitch skeletal muscle of the mouse', Amino Acids, vol. 31, no. 3, pp. 273-278.
• Lee, C, Herlt, A, Simpson, G et al. 2006, '4-Alkoxycarbonyl- and aminocarbonyl-substituted isoxazoles as masked acrylates and acrylamides in the asymmetric synthesis of Δ²-isoxazolines', Journal of Organic Chemistry, vol. 71, no. 8, pp. 3221-3231.
• Easton, C, Harper, J & Lincoln, S 2006, 'A molecular reactor for the synthesis of indirubin and related compounds', in L. Meijer, N. Guyard, L. Skaltsounis and G. Eisenbrand (ed.), Indirubin, the red shade of indigo, Life in Progress Editions, Roscoff, France, pp. 127-134.
• Altin, J, Banwell, M, Coghlan, P et al. 2006, 'Synthesis of NTA₃-DTDA - A Chelator-Lipid that Promotes Stable Binding of His-Tagged Proteins to Membranes', Australian Journal of Chemistry, vol. 59, no. 5, pp. 302-306.
• O'Connell, J, Simpson, J, Dumanski, P et al. 2006, 'Aromatic chlorination of ω-phenylalkylamines and ω-phenylalkylamides in carbon tetrachloride and α,α,α-trifluorotoluene', Organic and Biomolecular Chemistry, vol. 4, no. 14, pp. 2716-2723.
• Ferrante, A, Robinson, B, Singh, H et al. 2006, 'A novel β-oxa polyunsaturated fatty acid downregulates the activation of the IκB kinase/nuclear factor κB pathway, inhibits expression of endothelial cell adhesion molecules, and depresses inflammation', Circulation Research, vol. 99, no. 1, pp. 34-41.
• Coote, M, Easton, C & Zard, S 2006, 'Factors Affecting the Relative and Absolute Rates of β-Scission of Alkoxythiocarbonyl Radicals and Alkoxycarbonyl Radicals', Journal of Organic Chemistry, vol. 71, no. 13, pp. 4996-4999.
• Wood, G, Easton, C, Rauk, A et al. 2006, 'Effect of side chains on competing pathways for β-scission reactions of peptide-backbone alkoxyl radicals', Journal of Physical Chemistry A, vol. 110, no. 34, pp. 10316-10323.
• Cieslinski, M, Steel, P, Lincoln, S et al. 2006, 'Centrosymmetric and non-centrosymmetric packing of aligned molecular fibers in the solid state self assemblies of cyclodextrin-based rotaxanes', Supramolecular Chemistry, vol. 18, no. 6, pp. 529-536.
• Philbrook, A, Dunlop, N, Easton, C et al. 2006, 'Demonstration of crosslinking in melamine-urea-formaldehyde and cellulose-urea-formaldehyde reactions using ¹⁵N NMR correlation spectroscopy', Wood Adhesives Symposium 2005, ed. C R Frihart, Forest Products Society, Madison WI USA, pp. 143-147.
• Wee, S, Mortimer, A, Moran, D et al. 2006, 'Gas-phase regiocontrolled generation of charged amino acid and peptide radicals', Chemical Communications, vol. 2006/40, pp. 4233-4235.
• Philbrook, A, Earnshaw, S, Easton, C et al. 2006, 'Co-polymerization studies of wood resins using ¹⁵N NMR correlation spectroscopy', European Panel Products Symposium 2006, ed. Paul Fowler, University of Wales, Bangor, Wales, UK, pp. 47-57.
• Coulston, R, Onagi, H, Lincoln, S et al. 2006, 'Harnessing the energy of molecular recognition in a nanomachine having a photochemical on/off switch', Journal of the American Chemical Society, vol. 128, no. 46, pp. 14750-14751.
• Moran, D, Jacob, R, Wood, G et al. 2006, 'Rearrangements in model peptide-type radicals via intramolecular hydrogen-atom transfer', Helvetica Chimica Acta, vol. 89, no. 10, pp. 2254-2272.
• Barr, L, Lincoln, S & Easton, C 2006, 'Reversal of regioselectivity and enhancement of rates of nitrile oxide cycloadditions through transient attachment of dipolarophiles to cyclodextrins', Chemistry, A European Journal, vol. 12, no. 33, pp. 8571-8580.
• Lee, C, Easton, C, Savage, G et al. 2006, 'Synthesis of spiroisoxazolines through cycloadditions of nitrile oxides with 3-methylenequinuclidine', ARKIVOC, vol. 2006, no. iii, pp. 175-183.
• Easton, C 2005, 'Cyclodextrin-based catalysts and molecular reactors', Pure and Applied Chemistry, vol. 77, no. 11, pp. 1865-1871.
• Barr, L, Lincoln, S & Easton, C 2005, 'A cyclodextrin molecular reactor for the regioselective synthesis of 1,5-disubstituted-1,2,3-triazoles', Supramolecular Chemistry, vol. 17, no. 7, pp. 547-555.
• Costabile, M, Hii, C, Melino, M et al. 2005, 'The immunomodulatory effects of novel β-oxa, β-thia, and γ-thia polyunsaturated fatty acids on human T lymphocyte proliferation, cytokine production, and activation of protein kinase C and MAPKs', Journal of Immunology, vol. 174, no. 1, pp. 233-243.
• Ashnagar, A, Easton, C & Gharib Naseri, N 2005, 'Determination of association constants of β-cyclodextrin and β-cyclodextrin-N-succinamate with drugs by high performance liquid chromatography', Asian Journal of Chemistry, vol. 17, no. 1, pp. 183-190.
• May, B, Gausia, K, Clements, P et al. 2005, 'Cyclodextrin and modified cyclodextrin complexes of E-4-tert-butylphenyl-4-oxyazobenzene: UV-visible, ¹H NMR and ab initio studies', Organic and Biomolecular Chemistry, vol. 3, no. 8, pp. 1481-1488.
• Barr, L, Easton, C, Lee, K et al. 2005, 'Aminocyclodextrins to facilitate the deprotonation of 4-tert-butyl-α-nitrotoluene', Organic and Biomolecular Chemistry, vol. 3, no. 16, pp. 2990-2993.
• Philbrook, A, Blake, C, Dunlop, N et al. 2005, 'Demonstration of co-polymerization in melamine�urea�formaldehyde reactions using ¹⁵N NMR correlation spectroscopy', Polymer, vol. 46, no. 7, pp. 2153-2156.
• Topf, M, Sandala, G, Smith, D et al. 2004, 'The Unusual Bifunctional Catalysis of Epimerization and Desaturation by Carbapenem Synthase', Journal of the American Chemical Society, vol. 126, no. 32, pp. 9932-9933.
• Coghlan, P & Easton, C 2004, 'β-Nitro-α-amino Acids as Latent α,β-Dehydro-α-amino Acid Residues in Solid-Phase Peptide Synthesis', ARKIVOC, vol. 2004, no. x, pp. 101-108.
• Barratt, B, Easton, C, Henry, D et al. 2004, 'Inhibition of Peptidylglycine α-Amidating Monooxygenase by Exploitation of Factors Affecting the Stability and Ease of Formation of Glycyl Radicals', Journal of the American Chemical Society, vol. 126, no. 41, pp. 13306-13311.
• Easton, C, Lincoln, S, Barr, L et al. 2004, 'Molecular Reactors and Machines: Applications, Potential, and Limitations', Chemistry, A European Journal, vol. 10, no. 13, pp. 3120-3128.
• Barr, L, Dumanski, P, Easton, C et al. 2004, 'Cyclodextrin Molecular Reactors', Journal of Inclusion Phenomena and Macrocyclic Chemistry, vol. 50, no. 1, pp. 19-24.
• Lock, J, May, B, Clements, P et al. 2004, 'Cyclodextrin Complexation of the Stilbene 4-(2-(4-tert-Butylphenyl)ethen-1-yl)benzoate and the Self-assembly of Molecular Devices', Journal of Inclusion Phenomena and Macrocyclic Chemistry, vol. 50, no. 1, pp. 13-18.
• Lock, J, May, B, Clements, P et al. 2004, 'Cyclodextrin Complexation of a Stilbene and the Self-Assembly of a Simple Molecular Device', Organic and Biomolecular Chemistry, vol. 2, no. 3, pp. 337-344.
• Lock, J, May, B, Clements, P et al. 2004, 'Intra- and Intermolecular Complexation in C(6) Monoazacoronand Substituted Cyclodextrins', Organic and Biomolecular Chemistry, vol. 2, no. 9, pp. 1381-1386.
• Croft, A & Easton, C 2004, 'Anchimeric Assistance in Hydrogen-Atom Transfer to Bromine', Australian Journal of Chemistry, vol. 57, no. 7, pp. 651-654.
• Wyness, O, May, B, Clements, P et al. 2004, 'Diazacoronand-Linked α- and β-Cyclodextrin Dimer Complexes of the Brilliant Yellow Tetraanion', Australian Journal of Chemistry, vol. 57, no. 6, pp. 571-576.
• Barratt, B, Easton, C & Simpson, J 2004, Enzyme inhibitors, WO2004007417, Australia.
• Crasto, C, Forrest, A, Karoli, T et al. 2003, 'Synthesis and Activity of Analogues of the Isoleucyl tRNA Synthetase Inhibitor SB-203207', Bioorganic and Medicinal Chemistry, vol. 11, no. 13, pp. 2687-2694.
• Coghlan, D, Easton, C & Tiekink, E 2003, 'Crystal structure of meso-dimethyl 2,3-dibenzamido-2,3-dimethylbutanedioate, C₂₂H₂₄N₂O₆', Zeitschrift fur Kristallographie - New Crystal Structures, vol. 218, no. 3, pp. 359-360.
• Easton, C, Hughes, C & Tiekink, E 2003, 'Crystal structure of 3-(2,6-dichlorophenyl)-4,5-dihydro-7H-pyrano[4,3-d]isoxazol-7-one, C₁₂H₇C_l2NO₃', Zeitschrift fur Kristallographie - New Crystal Structures, vol. 218, no. 3, pp. 365-366.
• Onagi, H, Blake, C, Easton, C et al. 2003, 'Installation of a ratchet tooth and pawl to restrict rotation in a cyclodextrin rotaxane', Chemistry, A European Journal, vol. 9, no. 24, pp. 5978-5988.
• Coghlan, D, Easton, C & Tiekink, E 2003, 'Crystal structure of dl-dimethyl 2,3-dibenzamido-2,3-dimethylbutanedioate, C₂₂H₂₄N₂O₆', Zeitschrift fur Kristallographie - New Crystal Structures, vol. 218, no. 3, pp. 361-362.
• Onagi, H, Carrozzini, B, Cascarano, G et al. 2003, 'Separated and aligned molecular fibres in solid state self-assemblies of cyclodextrin [2]rotaxanes', Chemistry, A European Journal, vol. 9, no. 24, pp. 5971-5977.
• Dumanski, P, Easton, C, Lincoln, S et al. 2003, 'Effect of Cyclodextrins on Elelctrophilic Aromatic Bromination in Aqueous Solution', Australian Journal of Chemistry, vol. 56, no. 11, pp. 1107-1111.
• Harper, J, Easton, C & Lincoln, S 2003, 'A cyclodextrin-based molecular reactor to template the formation of indigoid dyes', Tetrahedron Letters, vol. 44, no. 31, pp. 5815-5818.
• Robinson, S, Rathjen, D, Trout, N et al. 2003, 'Inhibition of Neutrophil Leukotriene B₄ Production by a Novel Synthetic N-3 Polyunsaturated Fatty Acid Analogue, β-Oxa 21:3n-3', Journal of Immunology, vol. 171, no. 9, pp. 4773-4779.
• West, L, Wyness, O, May, B et al. 2003, 'Diazacoronand linked β-cyclodextrin dimer complexes of Brilliant Yellow tetraanion and their sodium(I) analogues', Organic and Biomolecular Chemistry, vol. 1, no. 5, pp. 887-894.
• Croft, A, Easton, C, Kociuba, K et al. 2003, 'Strategic use of amino acid N-substituents to limit α-carbon-centered radical formation and consequent loss of stereochemical integrity', Tetrahedron: Asymmetry, vol. 14, no. 19, pp. 2919-2926.
• Croft, A, Easton, C & Radom, L 2003, 'Design of Radical-Resistant Amino Acid Residues: A Combined Theoretical and Experimental Investigation', Journal of the American Chemical Society, vol. 125, no. 14, pp. 4119-4124.
• Easton, C, Edwards, A, McNabb, S et al. 2003, 'Allylic halogenation of unsaturated amino acids', Organic and Biomolecular Chemistry, vol. 1, no. 14, pp. 2492-2498.
• Brown, S, Easton, C & Kelly, J 2003, 'Surface plasmon resonance to determine apparent stability constants for the binding of cyclodextrins to small immobilized guests', Journal of Inclusion Phenomena and Macrocyclic Chemistry, vol. 46, no. 3-4, pp. 167-173.
• Easton, C, Hughes, C & Tiekink, E 2003, 'Crystal structure of 3-(2,6-dichlorophenyl)-6,7-dihydro-4H-pyrano[3,4-d]isoxazol-4-one, C₁₂H₇C_l2NO₃', Zeitschrift fur Kristallographie - New Crystal Structures, vol. 218, no. 3, pp. 363-364.
• Barr, L, Easton, C, Lee, K et al. 2002, 'Metallocyclodextrin catalysts for hydrolysis of phosphate triesters', Tetrahedron Letters, vol. 43, no. 43, pp. 7797-7800.
• Lee, C, Easton, C, Gebara-Coghlan, M et al. 2002, 'Substituent effects in isoxazoles: identification of 4-substituted isoxazoles as Michael acceptors', Journal of the Chemical Society, Perkin Transactions 2, vol. n/a, no. 12, pp. 2031-2038.
• Easton, C, Ferrante, A, Robertson, T et al. 2002, 'Antioxidant behaviour of thia fatty acids', Australian Journal of Chemistry, vol. 55, no. 10, pp. 647-653.
• Cieslinski, M, Clements, P, May, B et al. 2002, 'Complexation by α- and β-cyclodextrin C(6) linked homo- and hetero-dimers of Brilliant Yellow tetraanion: a study of host-guest size relationships', Journal of the Chemical Society, Perkin Transactions 2, vol. n/a, no. 5, pp. 947-952.
• Easton, C 2002, 'Cyclodextrins: Industrial Waste with Applications in Pharmacy, Catalysis and Microelectronics', Chemistry in New Zealand, vol. 66, pp. 49-52.
• Altin, J, White, F & Easton, C 2001, 'Synthesis of the chelator lipid nitrilotriacetic acid ditetradecylamine (NTA-DTDA) and its use with the IAsys biosensor to study receptor-ligand interactions on model membranes', Biochimica et Biophysica Acta: Biomembranes, vol. 1513, no. 2, pp. 131-148.
• Costabile, M, Hii, C, Robinson, B et al. 2001, 'A novel long chain polyunsaturated fatty acid, β-oxa 21:3n-3, inhibits T lymphocyte proliferation, cytokine production, delayed-type hypersensitivity, and carrageenan-induced paw reaction and selectively targets intracellular signals', Journal of Immunology, vol. 167, no. 7, pp. 3980-3987.
• Easton, C, Heath, G, Hughes, C et al. 2001, 'Electrochemical and yeast-catalyzed ring opening of isoxazoles in the synthesis of analogues of the herbicide Grasp', Journal of the Chemical Society, Perkin Transactions 1, vol. Issue 10, pp. 1168-1174.
• Easton, C, Hughes, C, Lincoln, S et al. 2001, 'Effect of beta-cyclodextrin on the extraction of isoxazolines from aqueous ethanol into chloroform', ARKIVOC, vol. 2, no. 12, pp. ms4.
• Easton, C, Harper, J, Head, S et al. 2001, 'Cyclodextrins to limit substrate inhibition and alter substrate selectivity displayed by enzymes', Journal of the Chemical Society, Perkin Transactions 1, vol. Issue 6, pp. 584-587.
• Kean, S, Easton, C, Lincoln, S et al. 2001, 'A preparative and solution study of a modified & beta-cyclodextrin, its europium (III) complex, and their interactions with racemic amino acid anions', Australian Journal of Chemistry, vol. 54, no. 8, pp. 535-539.
• Easton, C, Fryer, N, Kelly, J et al. 2001, 'Stereocontrolled synthesis of deuterated phenylalanine derivatives through manipulation of an N-phthaloyl protecting group for the recall of stereochemistry. Application in the study of phenylalanine ammonia lyase', ARKIVOC, vol. 2, no. 5, pp. ms7.
• Banwell, M, Crasto, C, Easton, C et al. 2001, 'Multi-component assembly of the bicyclic core associated with the tRNA synthetase inhibitors SB-203207 and SB-203208. Application to the synthesis of biologically active analogues', Chemical Communications, vol. Issue 21, pp. 2210-2211.
• Lock, J, May, B, Clements, P et al. 2001, 'Size discrimination in intramolecular complexation of modified α�cyclodextrins: a preparative and nuclear magnetic resonance study', Journal of the Chemical Society, Perkin Transactions 1, vol. Issue 24, pp. 3361-3364.
• Easton, C, Robertson, T, Pitt, M et al. 2001, 'Oxidation of oxa and thia fatty acids and related compounds catalyzed by 5- and 15-lipoxygenase', Bioorganic and Medicinal Chemistry, vol. 9, no. 2, pp. 317-322.
• Onagi, H, Easton, C & Lincoln, S 2001, 'An hermaphrodite [2]rotaxane: preparation and analysis of structure', Organic Letters, vol. 3, no. 7, pp. 1041-1044.
• Easton, C 2001, 'Modifications on amino acids and peptides via radicals', in P. Renaud and M. P. Sibi (ed.), Radicals in Organic Synthesis. Volume 2: Applications, Wiley-VCH Verlag GMBH, Weinheim, Germany, pp. 505-522.
• Meyer, A, Dai, L, Chen, Q et al. 2001, 'Selective adsorption of nitro-substituted aromatics and accelerated hydrolysis of 4-nitrophenyl acetate on carbon surfaces', New Journal of Chemistry, vol. 25, no. 7, pp. 887-889.
• Ferrante, A, Easton, C & Hii, C 2001, Anti-cancer nitro- and thia- fatty acids.
• Ferrante, A, Easton, C & Xia, L 2001, Anti-inflammatory nitro- and thia- fatty acids.
• Easton, C, Xia, L, Pitt, M et al. 2001, 'Polyunsaturated nitroalkanes and nitro-substituted fatty acids', Synthesis, vol. Issue 3, pp. 451-457.
• Kean, S, Easton, C & Lincoln, S 2000, 'Metallo-b-cyclodextrins of 6A-(2-(2-(2-Aminoethylamino)ethylamino)ethylamino)-6A-deoxy-b-cyclodextrin and 6A-Deoxy-6A-(1,4,7,10-tetraazacyclododecan-1-yl)-b-cyclodextrin', Australian Journal of Chemistry, vol. 53, no. 5, pp. 375-381.
• Headlam, H, Mortimer, A, Easton, C et al. 2000, 'b-Scission of C-3 (b-Carbon) Alkoxyl Radicals on Peptides and Proteins: A Novel Pathway Which Results in the Formation of a-Carbon Radicals and the Loss of Amino Acid Side Chains', Chemical Research in Toxicology, vol. 13, no. 11, pp. 1087-1095.
• May, B, Clements, P, Tsanaktsidis, J et al. 2000, 'Square pegs in round holes. Preparation and intramolecular complexation of cubyl substituted b-cyclodextrins and of an adamantane analog', Journal of the Chemical Society, Perkin Transactions 1, vol. 3, pp. 463-469.
• Walker, I, Easton, C & Ollis, D 2000, 'Site-directed mutagenesis of dienelactone hydrolase produces dienelactone isomerase', Chemical Communications, vol. 8, pp. 671-672.
• Banwell, M, Crasto, C, Easton, C et al. 2000, 'Analogues of SB-203207 as Inhibitors of tRNA Synthetases', Bioorganic and Medicinal Chemistry Letters, vol. 10, no. 20, pp. 2263-2266.
• Harper, J, Easton, C & Lincoln, S 2000, 'Cyclodextrins to Increase the Utility of Enzymes in Organic Synthesis', Current Organic Chemistry, vol. 4, no. 4, pp. 429-454.
• Easton, C, Merrett, M & Razzino, P 2000, 'Mechanism of hydrogen atom transfer in the photolytic rearrangement of N-bromophenylalaninamide derivatives', Journal of the Chemical Society, Perkin Transactions 2, vol. n/a, no. 4, pp. 693-697.
• Coghlan, D, Easton, C & Tiekink, E 2000, 'Molecular Recognition on Crystallization of Enantiopure and Racemic N-Benzoylalanine Methyl Ester', Australian Journal of Chemistry, vol. 53, no. 7, pp. 551-556.
• Sandow, M, May, B, Easton, C et al. 2000, 'Binary and Ternary Metallo-b-cyclodextrins of 6A-[Bis(carboxylatomethyl)amino]-6A-deoxy-b-cyclodextrin', Australian Journal of Chemistry, vol. 53, no. 2, pp. 149-152.
• Field, M, May, B, Clements, P et al. 2000, 'Intramolecular complexation in modified b-cyclodextrins: a preparative, nuclear magnetic resonance and pH titration study', Journal of the Chemical Society, Perkin Transactions 1, vol. n/a, no. 8, pp. 1251-1258.
• Easton, C & Peters, S 1999, 'a-Benzoyloxy- and a-methoxy-substituted glycine derivatives as atypical substrates for free-radical reactions with stannanes', Phosphorus, Sulfur, and Silicon and the Related Elements, vol. 150-151, pp. 57-166.
• Coghlan, P & Easton, C 1999, 'b-nitro-a-amino acids as latent a,b-dehydro-a-amino acid residues in peptides', Tetrahedron Letters, vol. 40, pp. 4745-4748.
• Coghlan, P & Easton, C 1999, 'A one-pot three component synthesis of b-nitro-a-amino acids and their N-alkyl derivatives', Royal Chemical Society Journal Perkin Transactions, pp. 2659-2660.
• Easton, C, Lincoln, S, Meyer, A et al. 1999, 'Synthesis and conformational analysis of an a-cyclodextrin [2]-rotaxane', Royal Chemical Society Journal Perkin Transactions, pp. 2501-2506.
• Kean, S, May, B, Clements, P et al. 1999, 'Host-guest complexation of aromatic carboxylic acids and their conjugate bases by 6A-(w-aminoalkyl)amino-6A-deoxy-b-cyclodextrins in aqueous solution', Royal Chemical Society Journal Perkin Transactions, pp. 1257-1263.
• Redman, K, May, B, Kean, S et al. 1999, 'Deacylation of 4-nitrophenyl acetate by 6A-(w-aminoalkyl)amino-6A-deoxy-b-cyclodextrins', Journal of the Chemical Society, Perkin Transactions 2, pp. 1711-1717.
• Robinson, B, Huang, Z, Parashakis, G et al. 1999, 'Effects of b-oxa and b-thia polyunsaturated fatty acids on agonist-induced increase in endothelial cell adhesion molecules', Lipids, vol. 34, pp. S341?S342.

Projects and Grants

Grants information is drawn from ARIES. To add or update Projects or Grants information please contact your College Research Office.

• Synthetic biology devices for streamlined nucleic acid amplification and detection at point-of-care (Secondary Investigator)
• Just-add-water nucleic acid amplification (Secondary Investigator)
• National Agricultural and Environment Sciences Precinct (Secondary Investigator)
• Flow Reactor Chemical Synthesis Facility (Secondary Investigator)
• Exploitation of unusual patterns of reactivity of peptides towards radicals (Primary Investigator)
• Studies of peptide hormones directed towards therapies for human cancers (Primary Investigator)
• Enzymatic Nutrition (Externally Led by CSIRO) (Primary Investigator)
• Design and synthesis of operating molecular machines and solution and solid-state devices (Primary Investigator)
• Biotechnological solutions to Australia's transport energy and greenhouse gas challenges (Primary Investigator)
• Regional Facility for Molecular Characterization and Mapping (Secondary Investigator)
• Bio-routes to fertilisers (Primary Investigator)
• Platform Technologies for the Regulation of Peptide Hormones (Primary Investigator)
• ARC Centre of Excellence - Centre for Free Radical Chemistry and Biotechnology (Primary Investigator)