Associate Professor Nicolas Cherbuin
Areas of expertise
- Mental Health 111714
- Epidemiology 111706
- Geriatrics And Gerontology 110308
- Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology) 170101
- Neurosciences 1109
- Developmental Psychology And Ageing 170102
Dr Cherbuin's main interests relate to the investigation of genetic, environmental, health, lifestyle, and personality factors which influence brain structure and plasticity throughout the lifespan but particularly in ageing populations and to study how cerebral structure and changes in structure relate to cognition and degenerative diseases. To research these questions he uses manual and semi-automated methods to measure and describe brain structures on MRI scans as well as to visualise 3D models of individual brains. The associations between these and other measures (e.g. memory, clinical diagnoses, age, handedness, etc) is subsequently investigated using typical statistical packages or specialised software. Another research focus is the early screening and identification of individuals at risk of cognitive impairment and dementia as well as the identification of associated risk and protective factors. This research is partly conducted in collaboration with the Dementia Collaborative Research Centres (DCRC) and Alzheimers Australia. Nic also has a keen interest in cerebral lateralisation and handedness.
Dr Cherbuin is an ARC Future Fellow and heads the NeuroIMaging and Brain Lab (NIMBL) at the Centre for Research on Ageing, Health and Wellbeing. He was awarded a PhD in 2006 at ANU. His doctoral thesis focused on factors affecting hemispheric interactions. From 2006 until 2008 he was the recipient of an Alzheimer's Australia Research and CMHR Fellowship. In 2007, he was awarded a NHMRC Fellowship to investigate associations between pre-frontal function and structure and cognition. Nic's current fellowship is focused on investigating theoretical models of age- and disease-related changes in brain structure and cognition.
Nic is also a member of the Dementia Collaborative Research Centre II, a federal initiative focused on dementia early detection and prevention.
A number of potential PhD projects are available to motivated individuals with a background in Psychology, Neuroscience, and other related areas who are interested in investigating associations between cognition, health, laterality and cerebral structure using neuroimaging data
Mark Fraser (PhD candidate) is investigating hippocampal structure in normal ageing using longitudinal data from the PATH project
Hossein Tabatabaei (PhD candidate) researches structural brain changes detectable in the early stages of dementia.
Tianqi Zhang (PhD candidate) is characterising brain differences in type 2 diabetes using shape analysis, and longitudinal methods.
Daniela Oryace (PhD candidate) investigates the associations between the brain behaviour control system (BIS/BAS/FFFS) and their cerebral structural correlates.
Dr Prapti Gautam (PhD 2012). “An investigation into the structural variability of the prefrontal cortex and its relationship to cognition and ageing”
Grants are drawn from ARIES. To add Projects or Grants please contact your College Research Office.
- Financial decision making in late adulthood (External led by QUT) (Secondary Investigator)
- Mental health and the PATH to midlife (Secondary Investigator)
- Centre of Research Excellence in Cognitive Health: Evidence, intervention and population modelling (Secondary Investigator)
- Development and validation of short forms of the Australian National University Alzheimer's Disease Risk Index (ANU-ADRI) - KT-EDP1 (Secondary Investigator)
- Too sweet for our own good (Primary Investigator)
- Functional and phenotypic effect of dopamine transporter gene variation (Secondary Investigator)
- What is normal brain ageing? An investigation of changes in brain structure and cognition in mid-life (Primary Investigator)
- Brain ageing from mid-life to old age: testing theoretical models of age and disease related changes to inform prevention (Primary Investigator)
- Improving methods of grading, transferring and facilitating translation of knowledge in population health (Secondary Investigator)
- High risk prescribing in older Australians: prevalence, outcomes and potential for intervention (Primary Investigator)
- Causes and consequences of mental disorders, cognitive decline and dementia over the adult life course and the implications for mental health services: PATH Through Life Wave 4 (Secondary Investigator)
- An investigation of the role of the pre-frontal cortex in cognitive ageing and dementia (Primary Investigator)