Skip navigation
The Australian National University

Dr Gaetan Burgio

MSc (Paris XI), MBBS (Paris VII), MD (Paris VII), PhD (Pasteur Institute and MNHN, Paris),
Group leader and head of the transgenesis facility, John Curtin School of Medical Research (JCSMR)
ANU College of Health and Medicine
T: +61 2 6125 9428

Areas of expertise

  • Genetics 0604
  • Quantitative Genetics (Incl. Disease And Trait Mapping Genetics) 060412
  • Haematology 110202
  • Infectious Diseases 110309
  • Genetics Not Elsewhere Classified 060499
  • Bacteriology 060501
  • Other Biological Sciences 0699
  • Medical Molecular Engineering Of Nucleic Acids And Proteins 100403

Research interests

Resistance from pathogens to antibiotics or antiparasitic drugs is a growing concern and affects millions patients worldwide every year. There is an urgent need to find novel treatment to improve the care of people as bacteria or parasites are becoming resistant to all existing antibiotics and antiparasitic agents. Novel & innovative strategies are desperately needed for this problem. In the general population, there are individual differences between humans that give some people an advantage in their ability to resist severe disease caused by infections. Our group aims to understand why these people are resistant to pathogens using mouse as a model. We use cutting-edge technologies (next-generation sequencing, genome editing) to study the biology of the interaction between the host and the pathogens.

Our group use CRISPR/Cas9 genome editing technology as a tool to study diseases with a specific focus on parasitic and bacterial infections. Our group also develops the technology and aims to better understand the editing and repair mechanisms. We are particularly interested on the mechanisms of Cas9 binding and repair after double strand break. As part of the Australian Phenomics Network our group provides to the scientific community CRISPR/Cas9 edited mice, advices on the technology and expertise on the development of the technology for specific applications. 

 

Biography

Dr Burgio was born in France and completed his education at Paris. He graduated from the Faculty of Medicine Xavier Bichat in Paris in 2002 with a Medical Doctor Degree. He worked as a consultant in an emergency department at Paris while he was undertaking his PhD studies at Pasteur Institute, Paris. He completed his PhD in 2008 from Pasteur Institute in France and migrated to Australia to join Professor Simon Foote as a postdoctoral researcher at the Menzies Research Institute (University of Tasmania) from 2008 to 2012 and the Australian School of Advanced Medicine at Macquarie University from 2012 to 2015 on the investigation of the host response to the malaria parasite using large scale ENU mitagenesis in mice. In 2015 he was appointed as a group leader at the John Curtin of Medical Research and the head of the transgenesis core facility at the Australian Phenomics Facility to establish a new research program of the host pathogens interaction on multidrug resistant bacteria and the malaria parasite using cutting edge technologies such as CRISPR/Cas9 genome editing. His research is supported from the National Health and Medical Research Council (NHMRC) and the National Collaborative Research Infrastructure Strategy (NCRIS) in Australia.

Publications

Projects and Grants

Grants information is drawn from ARIES. To add or update Projects or Grants information please contact your College Research Office.

Return to top

Updated:  21 September 2018 / Responsible Officer:  Director (Research Services Division) / Page Contact:  Researchers