Areas of expertise
- Enzymes 060107
- Protein Trafficking 060108
- Receptors And Membrane Biology 060110
- Structural Biology (Incl. Macromolecular Modelling) 060112
- Synthetic Biology 060113
Publications
- Gade, M, Tan, L, Damry, A et al. 2021, 'Substrate Dynamics Contribute to Enzymatic Specificity in Human and Bacterial Methionine Adenosyltransferases', JACS Au, vol. 1, no. 12, pp. 2349-2360.
- Qureshi, A, Suades, A, Matsuoka, R et al. 2020, 'The molecular basis for sugar import in malaria parasites', Nature, vol. 578, pp. 321-325.
- Brock, J, Hamberg, M, Balagunaseelan, N et al. 2016, 'A dynamic Asp-Arg interaction is essential for catalysis in microsomal prostaglandin E2 synthase', PNAS - Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 4, pp. 972-977.
- Cebula, M, Turan, K, Sjodin, B et al 2016, 'Catalytic Conversion of Lipophilic Substrates by Phase constrained Enzymes in the Aqueous or in the Membrane Phase', Scientific Reports, vol. 6, no. 38316, pp. 1-8.
- Brock, J, Board, P & Oakley, A 2013, 'Structural insights into omega-class glutathione transferases: a snapshot of enzyme reduction and identification of a non-catalytic ligandin site', PLOS ONE (Public Library of Science), vol. 8, no. 4, pp. e60324-e60324.
- Zhou, H, Brock, J, Liu, D et al 2012, 'Structural Insights into the Dehydroascorbate Reductase Activity of Human Omega-Class Glutathione Transferases', Journal of Molecular Biology, vol. 420, no. 3, pp. 190-203.
- Zhou, H, Brock, J, Casarotto, M et al 2011, 'Novel folding and stability defects cause a deficiency of human glutathione transferase omega 1', Journal of Biological Chemistry, vol. 286, no. 6, pp. 4271-4279.
Projects and Grants
Grants information is drawn from ARIES. To add or update Projects or Grants information please contact your College Research Office.
- Ancestral enzyme engineering for designer fat products (Secondary Investigator)
- Australasian Synthetic Biology Challenge Program - Admin Assistant Funding (Primary Investigator)
- Bioengineering for high-yield production of plastic degrading enzymes - Work Order 6 (Primary Investigator)
- Replacing animal derived antibodies with synthetic nanobodies using yeast surfacedisplayin the fields of structural biology, biotechnology and me (Primary Investigator)
